Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education

Show simple item record Jelenkovic, Aline Sund, Reijo Yokoyama, Yoshie Latvala, Antti Sugawara, Masumi Tanaka, Mami Matsumoto, Satoko Freitas, Duarte L. Maia, Jose Antonio Knafo-Noam, Ariel Mankuta, David Abramson, Lior Ji, Fuling Ning, Feng Pang, Zengchang Rebato, Esther Saudino, Kimberly J. Cutler, Tessa L. Hopper, John L. Ullemar, Vilhelmina Almqvist, Catarina Magnusson, Patrik K. E. Cozen, Wendy Hwang, Amie E. Mack, Thomas M. Nelson, Tracy L. Whitfield, Keith E. Sung, Joohon Kim, Jina Lee, Jooyeon Lee, Sooji Llewellyn, Clare H. Fisher, Abigail Medda, Emanuela Nistico, Lorenza Toccaceli, Virgilia Baker, Laura A. Tuvblad, Catherine Corley, Robin P. Huibregtse, Brooke M. Derom, Catherine A. Vlietinck, Robert F. Loos, Ruth J. F. Burt, S. Alexandra Klump, Kelly L. Silberg, Judy L. Maes, Hermine H. Krueger, Robert F. McGue, Matt Pahlen, Shandell Gatz, Margaret Butler, David A. Harris, Jennifer R. Brandt, Ingunn Nilsen, Thomas S. Harden, K. Paige Tucker-Drob, Elliot M. Franz, Carol E. Kremen, William S. Lyons, Michael J. Lichtenstein, Paul Bartels, Meike van Beijsterveldt, Catharina E. M. Willemsen, Gonneke Oncel, Sevgi Y. Aliev, Fazil Jeong, Hoe-Uk Hur, Yoon-Mi Turkheimer, Eric Boomsma, Dorret Srensen, Thorkild I. A. Kaprio, Jaakko Silventoinen, Karri 2020-09-17T06:41:01Z 2020-09-17T06:41:01Z 2020-05-14
dc.identifier.citation Jelenkovic , A , Sund , R , Yokoyama , Y , Latvala , A , Sugawara , M , Tanaka , M , Matsumoto , S , Freitas , D L , Maia , J A , Knafo-Noam , A , Mankuta , D , Abramson , L , Ji , F , Ning , F , Pang , Z , Rebato , E , Saudino , K J , Cutler , T L , Hopper , J L , Ullemar , V , Almqvist , C , Magnusson , P K E , Cozen , W , Hwang , A E , Mack , T M , Nelson , T L , Whitfield , K E , Sung , J , Kim , J , Lee , J , Lee , S , Llewellyn , C H , Fisher , A , Medda , E , Nistico , L , Toccaceli , V , Baker , L A , Tuvblad , C , Corley , R P , Huibregtse , B M , Derom , C A , Vlietinck , R F , Loos , R J F , Burt , S A , Klump , K L , Silberg , J L , Maes , H H , Krueger , R F , McGue , M , Pahlen , S , Gatz , M , Butler , D A , Harris , J R , Brandt , I , Nilsen , T S , Harden , K P , Tucker-Drob , E M , Franz , C E , Kremen , W S , Lyons , M J , Lichtenstein , P , Bartels , M , van Beijsterveldt , C E M , Willemsen , G , Oncel , S Y , Aliev , F , Jeong , H-U , Hur , Y-M , Turkheimer , E , Boomsma , D , Srensen , T I A , Kaprio , J & Silventoinen , K 2020 , ' Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education ' , Scientific Reports , vol. 10 , no. 1 , 7974 .
dc.identifier.other PURE: 144616617
dc.identifier.other PURE UUID: 565497eb-b2d4-4e45-a685-731babe462e6
dc.identifier.other WOS: 000560040700031
dc.identifier.other ORCID: /0000-0003-1759-3079/work/80576252
dc.identifier.other ORCID: /0000-0002-6268-8117/work/80577203
dc.description.abstract Genetic factors explain a major proportion of human height variation, but differences in mean stature have also been found between socio-economic categories suggesting a possible effect of environment. By utilizing a classical twin design which allows decomposing the variation of height into genetic and environmental components, we tested the hypothesis that environmental variation in height is greater in offspring of lower educated parents. Twin data from 29 cohorts including 65,978 complete twin pairs with information on height at ages 1 to 69 years and on parental education were pooled allowing the analyses at different ages and in three geographic-cultural regions (Europe, North America and Australia, and East Asia). Parental education mostly showed a positive association with offspring height, with significant associations in mid-childhood and from adolescence onwards. In variance decomposition modeling, the genetic and environmental variance components of height did not show a consistent relation to parental education. A random-effects meta-regression analysis of the aggregate-level data showed a trend towards greater shared environmental variation of height in low parental education families. In conclusion, in our very large dataset from twin cohorts around the globe, these results provide only weak evidence for the study hypothesis. en
dc.format.extent 11
dc.language.iso eng
dc.relation.ispartof Scientific Reports
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject TWINS
dc.subject GROWTH
dc.subject CHILDREN
dc.subject PROJECT
dc.subject LOCI
dc.subject 3142 Public health care science, environmental and occupational health
dc.title Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education en
dc.type Article
dc.contributor.organization Clinicum
dc.contributor.organization Department of Public Health
dc.contributor.organization University of Helsinki
dc.contributor.organization Department of Social Research (2010-2017)
dc.contributor.organization Institute of Criminology and Legal Policy
dc.contributor.organization Institute for Molecular Medicine Finland
dc.contributor.organization Helsinki Inequality Initiative (INEQ)
dc.contributor.organization Population Research Unit (PRU)
dc.contributor.organization Center for Population, Health and Society
dc.contributor.organization Sociology
dc.description.reviewstatus Peer reviewed
dc.relation.issn 2045-2322
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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