Upper endoscopy for non-acute non-specific symptoms is seldom beneficial for children under the age of seven

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http://hdl.handle.net/10138/319488

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Helin , N , Kolho , K-L , Rintala , R & Merras-Salmio , L 2020 , ' Upper endoscopy for non-acute non-specific symptoms is seldom beneficial for children under the age of seven ' , Acta Paediatrica , vol. 109 , no. 4 , pp. 827-835 . https://doi.org/10.1111/apa.15027

Title: Upper endoscopy for non-acute non-specific symptoms is seldom beneficial for children under the age of seven
Author: Helin, Noora; Kolho, Kaija-Leena; Rintala, Risto; Merras-Salmio, Laura
Contributor: University of Helsinki, Children's Hospital
University of Helsinki, Children's Hospital
University of Helsinki, HUS Children and Adolescents
University of Helsinki, Clinicum
Date: 2020-04
Language: eng
Number of pages: 9
Belongs to series: Acta Paediatrica
ISSN: 0803-5253
URI: http://hdl.handle.net/10138/319488
Abstract: Abstract Aim This study estimated the diagnostic yield of oesophagogastroduodenoscopy (OGD) in young children with non-acute, non-specific gastrointestinal or respiratory symptoms who were treated by a Finnish tertiary level referral centre. Methods A retrospective chart analysis was performed on 1850 Finnish children under seven years of age who underwent their first diagnostic OGDs at Helsinki University Hospital during 2006-2016. We noted the endoscopy indications, macroscopic findings, the histology of the mucosal biopsies and the follow-up data. Results After the exclusion criteria were applied, we enrolled 666 patients (57.7% boys) at a median age of 3.5 years. The number of children with non-specific symptoms referred for OGD increased 2.3-fold in 11 years. A routine set of biopsies was obtained in 644/666 (96.7%) of the endoscopies. The OGD was both macroscopically and histologically normal in 519/644 (80.6%) of cases. The most common indication was to rule out gastro-oesophageal reflux disease in 268/666 (40.2%) cases and the most frequent histological diagnosis was mild to moderate oesophagitis in 57/644 (8.9%) cases. There was no erosive oesophagitis. Conclusion The diagnostic yield of macroscopic and histological OGD findings was low in our cohort. Unless there are alarming symptoms, younger children do not need OGD.
Subject: Biopsy
Gastritis
Gastro-oesophageal reflux
Oesophagitis
Respiratory symptoms
EGD
EROSIVE ESOPHAGITIS
PREVALENCE
FUNCTIONAL GASTROINTESTINAL DISORDERS
CHILDHOOD
gastro-oesophageal reflux
respiratory symptoms
GASTROESOPHAGEAL-REFLUX DISEASE
biopsy
oesophagitis
gastritis
DIAGNOSTIC YIELD
EPIDEMIOLOGY
3123 Gynaecology and paediatrics
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