Subtype of atrial fibrillation and the outcome of transcatheter aortic valve replacement: The FinnValve Study

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dc.contributor.author Jaakkola, Jussi
dc.contributor.author Jaakkola, Samuli
dc.contributor.author Airaksinen, K. E. Juhani
dc.contributor.author Husso, Annastiina
dc.contributor.author Juvonen, Tatu
dc.contributor.author Laine, Mika
dc.contributor.author Virtanen, Marko
dc.contributor.author Maaranen, Pasi
dc.contributor.author Niemelä, Matti
dc.contributor.author Mäkikallio, Timo
dc.contributor.author Savontaus, Mikko
dc.contributor.author Tauriainen, Tuomas
dc.contributor.author Valtola, Antti
dc.contributor.author Vento, Antti
dc.contributor.author Eskola, Markku
dc.contributor.author Raivio, Peter
dc.contributor.author Biancari, Fausto
dc.date.accessioned 2020-09-21T07:07:01Z
dc.date.available 2020-09-21T07:07:01Z
dc.date.issued 2020-09-11
dc.identifier.citation Jaakkola , J , Jaakkola , S , Airaksinen , K E J , Husso , A , Juvonen , T , Laine , M , Virtanen , M , Maaranen , P , Niemelä , M , Mäkikallio , T , Savontaus , M , Tauriainen , T , Valtola , A , Vento , A , Eskola , M , Raivio , P & Biancari , F 2020 , ' Subtype of atrial fibrillation and the outcome of transcatheter aortic valve replacement: The FinnValve Study ' , PLoS One , vol. 15 , no. 9 , 0238953 . https://doi.org/10.1371/journal.pone.0238953
dc.identifier.other PURE: 144621040
dc.identifier.other PURE UUID: 43c9e026-d302-427b-9c79-9920a53d1a0c
dc.identifier.other RIS: urn:ACE8856749B9195B372398A0243F9F7C
dc.identifier.other WOS: 000571887500091
dc.identifier.uri http://hdl.handle.net/10138/319504
dc.description.abstract Whether the subtype of atrial fibrillation affects outcomes after transcatheter aortic valve replacement for aortic stenosis is unclear. The nationwide FinnValve registry included 2130 patients who underwent primary after transcatheter aortic valve replacement for aortic stenosis during 2008–2017. Altogether, 281 (13.2%) patients had pre-existing paroxysmal atrial fibrillation, 651 (30.6%) had pre-existing non-paroxysmal atrial fibrillation and 160 (7.5%) were diagnosed with new-onset atrial fibrillation during the index hospitalization. The median follow-up was 2.4 (interquartile range: 1.6–3.8) years. Paroxysmal atrial fibrillation did not affect 30-day or overall mortality (p-values >0.05). Non-paroxysmal atrial fibrillation demonstrated an increased risk of overall mortality (hazard ratio: 1.61, 95% confidence interval: 1.35–1.92; p0.05). In conclusion, non-paroxysmal atrial fibrillation and new-onset atrial fibrillation are associated with increased mortality after transcatheter aortic valve replacement for aortic stenosis, whereas paroxysmal atrial fibrillation has no effect on mortality. These findings suggest that non-paroxysmal atrial fibrillation rather than paroxysmal atrial fibrillation may be associated with structural cardiac damage which is of prognostic significance in patients with aortic stenosis undergoing transcatheter aortic valve replacement. en
dc.format.extent 12
dc.language.iso eng
dc.relation.ispartof PLoS One
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology
dc.subject CLINICAL-OUTCOMES
dc.subject INCREASED MORTALITY
dc.subject IMPLANTATION
dc.subject IMPACT
dc.subject STENOSIS
dc.subject MANAGEMENT
dc.subject RISK
dc.title Subtype of atrial fibrillation and the outcome of transcatheter aortic valve replacement: The FinnValve Study en
dc.type Article
dc.contributor.organization HUS Heart and Lung Center
dc.contributor.organization III kirurgian klinikka
dc.contributor.organization Clinicum
dc.contributor.organization Department of Surgery
dc.contributor.organization Kardiologian yksikkö
dc.contributor.organization Helsinki University Hospital Area
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1371/journal.pone.0238953
dc.relation.issn 1932-6203
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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