Protrudin in protrudinG invadopodia : Membrane contact sites and cell invasion
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Arora , A & Olkkonen , V M 2020 , ' Protrudin in protrudinG invadopodia : Membrane contact sites and cell invasion ' , Journal of Cell Biology , vol. 219 , no. 8 , 202006146 . https://doi.org/10.1083/jcb.202006146
| Title: | Protrudin in protrudinG invadopodia : Membrane contact sites and cell invasion |
| Author: | Arora, Amita; Olkkonen, Vesa M. |
| Contributor organization: | Medicum Faculty of Medicine University of Helsinki Biosciences Department of Anatomy |
| Date: | 2020-08-03 |
| Language: | eng |
| Number of pages: | 2 |
| Belongs to series: | Journal of Cell Biology |
| ISSN: | 0021-9525 |
| DOI: | https://doi.org/10.1083/jcb.202006146 |
| URI: | http://hdl.handle.net/10138/320481 |
| Abstract: | Invadopodia are dynamic protrusions that harbor matrix metalloproteinases for pericellular matrix degradation. However, the mechanisms underlying their maturation are poorly understood. Pedersen et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202003063) demonstrate a dual role of Protrudin in invadopodia elongation and matrix degradation, central to cell invasion and cancer metastasis. |
| Subject: | 1182 Biochemistry, cell and molecular biology |
| Peer reviewed: | No |
| Rights: | cc_by_nc_sa |
| Usage restriction: | openAccess |
| Self-archived version: | publishedVersion |
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Articles from TUHAT CRIS [46688]