Protrudin in protrudinG invadopodia : Membrane contact sites and cell invasion

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Arora , A & Olkkonen , V M 2020 , ' Protrudin in protrudinG invadopodia : Membrane contact sites and cell invasion ' , Journal of Cell Biology , vol. 219 , no. 8 , 202006146 . https://doi.org/10.1083/jcb.202006146

Titel: Protrudin in protrudinG invadopodia : Membrane contact sites and cell invasion
Författare: Arora, Amita; Olkkonen, Vesa M.
Medarbetare: University of Helsinki, Medicum
University of Helsinki, Medicum
Datum: 2020-08-03
Språk: eng
Sidantal: 2
Tillhör serie: Journal of Cell Biology
ISSN: 0021-9525
Permanenta länken (URI): http://hdl.handle.net/10138/320481
Abstrakt: Invadopodia are dynamic protrusions that harbor matrix metalloproteinases for pericellular matrix degradation. However, the mechanisms underlying their maturation are poorly understood. Pedersen et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202003063) demonstrate a dual role of Protrudin in invadopodia elongation and matrix degradation, central to cell invasion and cancer metastasis.
Subject: 1182 Biochemistry, cell and molecular biology
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