Short- and long-term survival after severe acute pancreatitis : A retrospective 17 years' cohort study from a single center

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http://hdl.handle.net/10138/320938

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Husu , H L , Leppäniemi , A K , Lehtonen , T M , Puolakkainen , P A & Mentula , P J 2019 , ' Short- and long-term survival after severe acute pancreatitis : A retrospective 17 years' cohort study from a single center ' , Journal of Critical Care , vol. 53 , pp. 81-86 . https://doi.org/10.1016/j.jcrc.2019.06.001

Title: Short- and long-term survival after severe acute pancreatitis : A retrospective 17 years' cohort study from a single center
Author: Husu, Henrik Leonard; Leppäniemi, Ari Kalevi; Lehtonen, Taru Marika; Puolakkainen, Pauli Antero; Mentula, Panu Juhani
Contributor: University of Helsinki, HUS Abdominal Center
University of Helsinki, HUS Abdominal Center
University of Helsinki, Clinicum
University of Helsinki, HUS Abdominal Center
University of Helsinki, Staff Services
Date: 2019-10
Language: eng
Number of pages: 6
Belongs to series: Journal of Critical Care
ISSN: 0883-9441
URI: http://hdl.handle.net/10138/320938
Abstract: Purpose: To study mortality in severe acute pancreatitis (SAP) and to identify risk factors for mortality. Materials and methods: A retrospective 17-years' cohort study of 435 consecutive adult patientswith SAP treated at intensive care unit of a university hospital. Results: Overall, 357 (82.1%) patients survived at 90 days follow-up. Three-hundred six (89.5%) patients under 60 years, 38 (60.3%) patients between 60 and 69 years, and 13 (43.3%) patients over 69 years of age survived at 90 days follow-up. Independent risk factors for death within 90-days were: 60 to 69 years of age (odds ratio [OR] 5.1), >69 years of age (OR 10.4), female sex (OR 2.0), heart disease (OR 2.9), chronic liver failure (OR 12.3), open abdomen treatment (OR 4.4) and sterile necrosectomy within 4 weeks (OR 14.7). The 10-year survival estimate was Conclusions: Although younger patients have excellent short-term survival after SAP, the long-term survival estimate is disappointing mostly due to alcohol abuse. (C) 2019 Elsevier Inc. All rights reserved.
Subject: Acute pancreatitis
Severe acute pancreatitis
Intensive care
Survival
Mortality
Alcohol abuse
ABDOMINAL COMPARTMENT SYNDROME
REVISED ATLANTA CLASSIFICATION
INTRAABDOMINAL HYPERTENSION
NECROTIZING PANCREATITIS
CLINICAL-RELEVANCE
MORTALITY
NECROSECTOMY
MANAGEMENT
OUTCOMES
3126 Surgery, anesthesiology, intensive care, radiology
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