Intraocular Lens Power, Myopia, and the Risk of Nd : YAG Capsulotomy after 15,375 Cataract Surgeries

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http://hdl.handle.net/10138/322165

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Lindholm , J-M , Laine , I & Tuuminen , R 2020 , ' Intraocular Lens Power, Myopia, and the Risk of Nd : YAG Capsulotomy after 15,375 Cataract Surgeries ' , Journal of clinical medicine , vol. 9 , no. 10 , 3071 . https://doi.org/10.3390/jcm9103071

Title: Intraocular Lens Power, Myopia, and the Risk of Nd : YAG Capsulotomy after 15,375 Cataract Surgeries
Author: Lindholm, Juha-Matti; Laine, Ilkka; Tuuminen, Raimo
Contributor: University of Helsinki, HUS Head and Neck Center
University of Helsinki, HUS Head and Neck Center
University of Helsinki, Medicum
Date: 2020-10
Language: eng
Number of pages: 7
Belongs to series: Journal of clinical medicine
ISSN: 2077-0383
URI: http://hdl.handle.net/10138/322165
Abstract: The present study estimated the 5-year cumulative probability of Nd:YAG laser posterior capsulotomy according to the diopter power of implanted hydrophobic acrylic intraocular lenses (IOLs). Data were retrospectively collected of 15,375 eyes having cataract surgery and in-the-bag implantation of hydrophobic acrylic monofocal IOLs at the Ophthalmology Unit of Kymenlaakso Central Hospital, Kotka, Finland between the years 2007 and 2016. The cumulative probability of Nd:YAG capsulotomy was calculated by Kaplan-Meier estimates, and potential risk factors were analyzed using the Cox proportional hazards model. The 5-year cumulative probability of Nd:YAG capsulotomy after cataract surgery was 27.4% (95% confidence interval (CI) 22.9-32.6%) for low-diopter (5-16.5 D) IOLs, 14.6% (13.8-15.5%) for mid-diopter (17-24.5 D) IOLs, and 13.6% (11.7-15.6%) for high-diopter (25-30 D) IOLs. A multivariate Cox regression analysis showed that low-diopter IOLs (HR 1.76; 95% CI 1.38-2.25; p <0.001) were associated with an increased risk of Nd:YAG capsulotomy compared to mid-diopter IOLs over the follow-up period after accounting for other predictors. Real-world evidence shows that low-diopter IOLs are associated with significantly higher risk of Nd:YAG capsulotomy within five years following implantation. Estimation should help in evaluating the risks of cataract surgery in myopic eyes.
Subject: cataract surgery
posterior capsule opacification
Nd
YAG capsulotomy
myopia
low-diopter IOL
retrospective cohort study
ZCB00
PCB00
SN60WF
ZA9003
LASER POSTERIOR CAPSULOTOMY
OPTIC EDGE
AXIAL LENGTH
OPACIFICATION
EYES
PHACOEMULSIFICATION
IMPLANTATION
SHARP
PROBABILITY
DETACHMENT
3125 Otorhinolaryngology, ophthalmology
3126 Surgery, anesthesiology, intensive care, radiology
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