Long-range phase synchronization of highfrequency oscillations in human cortex

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Arnulfo , G , Wang , S H , Myrov , V , Toselli , B , Hirvonen , J , Fato , MM , Nobili , L , Cardinale , F , Rubino , A , Zhigalov , A , Palva , S & Palva , M 2020 , ' Long-range phase synchronization of highfrequency oscillations in human cortex ' , Nature Communications , vol. 11 , no. 1 , 5363 . https://doi.org/10.1038/s41467-020-18975-8

Title: Long-range phase synchronization of highfrequency oscillations in human cortex
Author: Arnulfo, Gabriele; Wang, Sheng H.; Myrov, Vladislav; Toselli, Benedetta; Hirvonen, Jonni; Fato, MM; Nobili, L; Cardinale, F; Rubino, A; Zhigalov, Alexander; Palva, Satu; Palva, Matias
Contributor organization: Neuroscience Center
Helsinki Institute of Life Science HiLIFE
University of Helsinki
Faculty Common Matters
Matias Palva / Principal Investigator
Date: 2020-10-23
Language: eng
Number of pages: 15
Belongs to series: Nature Communications
ISSN: 2041-1723
DOI: https://doi.org/10.1038/s41467-020-18975-8
URI: http://hdl.handle.net/10138/322270
Abstract: Inter-areal synchronization of neuronal oscillations at frequencies below similar to 100Hz is a pervasive feature of neuronal activity and is thought to regulate communication in neuronal circuits. In contrast, faster activities and oscillations have been considered to be largely local-circuit-level phenomena without large-scale synchronization between brain regions. We show, using human intracerebral recordings, that 100-400Hz high-frequency oscillations (HFOs) may be synchronized between widely distributed brain regions. HFO synchronization expresses individual frequency peaks and exhibits reliable connectivity patterns that show stable community structuring. HFO synchronization is also characterized by a laminar profile opposite to that of lower frequencies. Importantly, HFO synchronization is both transiently enhanced and suppressed in separate frequency bands during a response-inhibition task. These findings show that HFO synchronization constitutes a functionally significant form of neuronal spike-timing relationships in brain activity and thus a mesoscopic indication of neuronal communication per se.
Subject: 3112 Neurosciences
AMPLITUDE CORRELATIONS
RIPPLE OSCILLATIONS
NEURONAL SYNCHRONY
FIELD POTENTIALS
VISUAL-CORTEX
BRAIN
MEMORY
EEG
HZ
MECHANISMS
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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