Cu(I) mediated degradation of polysaccharides leads to fragments with narrow polydispersities

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http://hdl.handle.net/10138/322369

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Rahkila , J , Ekholm , F S & Leino , R 2018 , ' Cu(I) mediated degradation of polysaccharides leads to fragments with narrow polydispersities ' , European Journal of Organic Chemistry , no. 12 , pp. 1449-1454 . https://doi.org/10.1002/ejoc.201800033

Title: Cu(I) mediated degradation of polysaccharides leads to fragments with narrow polydispersities
Author: Rahkila, Jani; Ekholm, Filip S.; Leino, Reko
Contributor: University of Helsinki, Department of Chemistry
Date: 2018-03-29
Language: eng
Number of pages: 6
Belongs to series: European Journal of Organic Chemistry
ISSN: 1434-193X
URI: http://hdl.handle.net/10138/322369
Abstract: Biomass derived oligo- and polysaccharides are important compounds for various applications, including biomedicine and material science. Their use, however, is often limited by inherent structural inhomogeneity of the starting materials. Here, a method for depolymerization of naturally occurring polysaccharides, including dextran, starch, xylan and galactoglucomannan, into well-defined fragments of narrow polydispersities is described, based on the use of in situ generated Cu-I species under the commonly employed CuAAC reaction conditions. The main strength of the reported method is its high versatility, both in terms of substrate scope and operational simplicity.
Subject: Oligosaccharides
Controlled depolymerization
Biomass
Renewable resources
Click chemistry
AUTOMATED OLIGOSACCHARIDE SYNTHESIS
CLICK CHEMISTRY
ASCORBIC-ACID
OXIDATIVE DEPOLYMERIZATION
COPPER
SPECTROSCOPY
FRACTIONS
MIXTURES
116 Chemical sciences
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