A descriptive study highlighting the differences in the treatment protocol for oral tongue cancer in Sweden and Finland

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http://hdl.handle.net/10138/323316

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Mäkitie , A , Kamali , A , Mroueh , R , Lindford , A , Koivunen , P , Autio , T , Lassus , P , Halle , M , Bäck , L , Palmgren , B & Hammarstedt-Nordenvall , L 2020 , ' A descriptive study highlighting the differences in the treatment protocol for oral tongue cancer in Sweden and Finland ' , Acta Oto-Laryngologica , vol. 140 , no. 2 , pp. 188-194 . https://doi.org/10.1080/00016489.2019.1699663

Titel: A descriptive study highlighting the differences in the treatment protocol for oral tongue cancer in Sweden and Finland
Författare: Mäkitie, Antti; Kamali, Alexander; Mroueh, Rayan; Lindford, Andrew; Koivunen, Petri; Autio, Timo; Lassus, Patrik; Halle, Martin; Bäck, Leif; Palmgren, Björn; Hammarstedt-Nordenvall, Lalle
Upphovmannens organisation: HUS Head and Neck Center
University Management
Department of Ophthalmology and Otorhinolaryngology
University of Helsinki
Research Program in Systems Oncology
Faculty of Medicine
Clinicum
Department of Oral and Maxillofacial Diseases
HUS Musculoskeletal and Plastic Surgery
Plastiikkakirurgian yksikkö
Datum: 2020-02-01
Språk: eng
Sidantal: 7
Tillhör serie: Acta Oto-Laryngologica
ISSN: 0001-6489
DOI: https://doi.org/10.1080/00016489.2019.1699663
Permanenta länken (URI): http://hdl.handle.net/10138/323316
Abstrakt: Background and aims: Stage II cancer of the tongue is mostly managed surgically both locally and regionally. However, indications for postoperative radiotherapy and reconstructive options vary between centers. This paper aims to describe differences in treatment in a geographically homogenous cohort. Methods: A retrospective comparison was made between two cohorts of clinical T2N0 tongue cancer from Finland and Sweden. The Finnish cohort included 75 patients and the Swedish 54. All patients had curative intent of treatment and no previous head and neck cancer. Data analyzed consisted of pathological stage, size and thickness of tumor, frequency of reconstruction, radiotherapy delivered, and survival. Results: The Finnish cohort included a higher proportion of patients managed with reconstructive surgery (67%) than the Swedish cohort (0%), p <.00001. More patients were treated with postoperative radiotherapy (84%) in the Swedish cohort than in the Finnish (54%), p <.0002. The Finnish cohort had a higher level of survival and included more frequent downstaging (cTNM to pTNM).
Subject: Tongue cancer
reconstruction
outcome
recurrence
SQUAMOUS-CELL CARCINOMA
QUALITY-OF-LIFE
LYMPH-NODES
RECONSTRUCTION
DETERMINANTS
RESECTION
SURVIVAL
BIOPSY
HEAD
3125 Otorhinolaryngology, ophthalmology
Referentgranskad: Ja
Licens: unspecified
Användningsbegränsning: openAccess
Parallelpublicerad version: acceptedVersion


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