Exhaled breath analysis in the diagnosis of head and neck cancer

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http://hdl.handle.net/10138/323511

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Mäkitie , A A , Almangush , A , Youssef , O , Metsälä , M , Silen , S , Nixon , I J , Haigentz , M , Rodrigo , J P , Saba , N F , Vander Poorten , V & Ferlito , A 2020 , ' Exhaled breath analysis in the diagnosis of head and neck cancer ' , Head & Neck , vol. 42 , no. 4 , pp. 787-793 . https://doi.org/10.1002/hed.26043

Title: Exhaled breath analysis in the diagnosis of head and neck cancer
Author: Mäkitie, Antti A.; Almangush, Alhadi; Youssef, Omar; Metsälä, Markus; Silen, Suvi; Nixon, Iain J.; Haigentz, Missak; Rodrigo, Juan P.; Saba, Nabil F.; Vander Poorten, Vincent; Ferlito, Alfio
Contributor: University of Helsinki, HUS Head and Neck Center
University of Helsinki, HUS Head and Neck Center
University of Helsinki, Department of Pathology
University of Helsinki, Department of Chemistry
University of Helsinki, Clinicum
Date: 2020-04
Language: eng
Number of pages: 7
Belongs to series: Head & Neck
ISSN: 1043-3074
URI: http://hdl.handle.net/10138/323511
Abstract: Head and neck cancer (HNC) comprises a heterogeneous group of upper aerodigestive tract malignant neoplasms, the most frequent of which is squamous cell carcinoma. HNC forms the eighth most common cancer type and the incidence is increasing. However, survival has improved only moderately during the past decades. Currently, early diagnosis remains the mainstay for improving treatment outcomes in this patient population. Unfortunately, screening methods to allow early detection of HNC are not yet established. Therefore, many cases are still diagnosed at advanced stage, compromising outcomes. Exhaled breath analysis (EBA) is a diagnostic tool that has been recently introduced for many cancers. Breath analysis is non-invasive, cost-effective, time-saving, and can potentially be applied for cancer screening. Here, we provide a summary of the accumulated evidence on the feasibility of EBA in the diagnosis of HNC.
Subject: diagnosis
exhaled breath analysis
head and neck cancer
VOLATILE ORGANIC-COMPOUNDS
SQUAMOUS-CELL CARCINOMA
CONDENSATE PH
BIOMARKERS
HPV
CONSTITUENTS
COLLECTION
DISEASE
MARKERS
3125 Otorhinolaryngology, ophthalmology
3126 Surgery, anesthesiology, intensive care, radiology
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