Exhaled breath analysis in the diagnosis of head and neck cancer

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dc.contributor.author Mäkitie, Antti A.
dc.contributor.author Almangush, Alhadi
dc.contributor.author Youssef, Omar
dc.contributor.author Metsälä, Markus
dc.contributor.author Silen, Suvi
dc.contributor.author Nixon, Iain J.
dc.contributor.author Haigentz, Missak
dc.contributor.author Rodrigo, Juan P.
dc.contributor.author Saba, Nabil F.
dc.contributor.author Vander Poorten, Vincent
dc.contributor.author Ferlito, Alfio
dc.date.accessioned 2020-12-18T23:32:25Z
dc.date.available 2021-12-18T03:45:55Z
dc.date.issued 2020-04
dc.identifier.citation Mäkitie , A A , Almangush , A , Youssef , O , Metsälä , M , Silen , S , Nixon , I J , Haigentz , M , Rodrigo , J P , Saba , N F , Vander Poorten , V & Ferlito , A 2020 , ' Exhaled breath analysis in the diagnosis of head and neck cancer ' , Head & Neck , vol. 42 , no. 4 , pp. 787-793 . https://doi.org/10.1002/hed.26043
dc.identifier.other PURE: 130209784
dc.identifier.other PURE UUID: 4b541fe5-595d-493a-a483-6b813c40cd20
dc.identifier.other WOS: 000503268700001
dc.identifier.other ORCID: /0000-0002-0716-7132/work/71182996
dc.identifier.other ORCID: /0000-0002-1827-9156/work/71184973
dc.identifier.uri http://hdl.handle.net/10138/323511
dc.description.abstract Head and neck cancer (HNC) comprises a heterogeneous group of upper aerodigestive tract malignant neoplasms, the most frequent of which is squamous cell carcinoma. HNC forms the eighth most common cancer type and the incidence is increasing. However, survival has improved only moderately during the past decades. Currently, early diagnosis remains the mainstay for improving treatment outcomes in this patient population. Unfortunately, screening methods to allow early detection of HNC are not yet established. Therefore, many cases are still diagnosed at advanced stage, compromising outcomes. Exhaled breath analysis (EBA) is a diagnostic tool that has been recently introduced for many cancers. Breath analysis is non-invasive, cost-effective, time-saving, and can potentially be applied for cancer screening. Here, we provide a summary of the accumulated evidence on the feasibility of EBA in the diagnosis of HNC. en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof Head & Neck
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject diagnosis
dc.subject exhaled breath analysis
dc.subject head and neck cancer
dc.subject VOLATILE ORGANIC-COMPOUNDS
dc.subject SQUAMOUS-CELL CARCINOMA
dc.subject CONDENSATE PH
dc.subject BIOMARKERS
dc.subject HPV
dc.subject CONSTITUENTS
dc.subject COLLECTION
dc.subject DISEASE
dc.subject MARKERS
dc.subject 3125 Otorhinolaryngology, ophthalmology
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology
dc.title Exhaled breath analysis in the diagnosis of head and neck cancer en
dc.type Review Article
dc.contributor.organization HUS Head and Neck Center
dc.contributor.organization Department of Ophthalmology and Otorhinolaryngology
dc.contributor.organization Research Program in Systems Oncology
dc.contributor.organization Research Programs Unit
dc.contributor.organization University of Helsinki
dc.contributor.organization Oral and Maxillofacial Surgery
dc.contributor.organization Department of Pathology
dc.contributor.organization Faculty of Medicine
dc.contributor.organization Medicum
dc.contributor.organization Department of Chemistry
dc.contributor.organization Clinicum
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1002/hed.26043
dc.relation.issn 1043-3074
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion

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