Bilateral low systolic toe pressure and toe-brachial index are associated with long-term mortality in patients with peripheral artery disease

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Wickström , J-E , Virtanen , J , Aro , E , Jalkanen , J , Venermo , M & Hakovirta , H 2019 , ' Bilateral low systolic toe pressure and toe-brachial index are associated with long-term mortality in patients with peripheral artery disease ' , Journal of Vascular Surgery , vol. 70 , no. 6 , pp. 1994-2004 . https://doi.org/10.1016/j.jvs.2019.03.073

Title: Bilateral low systolic toe pressure and toe-brachial index are associated with long-term mortality in patients with peripheral artery disease
Author: Wickström, Jan-Erik; Virtanen, Juha; Aro, Ellinoora; Jalkanen, Juho; Venermo, Maarit; Hakovirta, Harri
Contributor: University of Helsinki, HUS Abdominal Center
University of Helsinki, Verisuonikirurgian yksikkö
Date: 2019-12
Language: eng
Number of pages: 11
Belongs to series: Journal of Vascular Surgery
ISSN: 0741-5214
URI: http://hdl.handle.net/10138/323902
Abstract: Objective: Based on our previous reports, ipsilateral systolic toe pressure (STP) and toe-brachial index (TBI) have a strong association with midterm cardiovascular and overall mortality as well as with amputation-free survival in patients with symptomatic lower extremity peripheral artery disease (PAD). The effect of the often overlooked contralateral lower limb on patient outcome remains unknown. This study aimed to resolve the significance of contralateral STP (CL_STP) and contralateral TBI for long-term overall and cardiovascular mortality. Methods: This is a retrospective cohort study of 727 consecutive patients with symptomatic lower extremity PAD. All patients admitted to the Department of Vascular Surgery at Turku University Hospital for digital subtraction angiography between January 2009 and August 2011 and for whom STP measurements were available were recruited and observed for up to 7 years. Dates and causes of death were collected from the national cause of death registry of Statistics Finland. Results: In the study cohort, STP was Conclusions: Low STP and TBI of both contralateral and ipsilateral lower extremities are associated with high cardiovascular and overall mortality in symptomatic PAD patients. Bilaterally low STP and TBI are associated with a particularly poor prognosis.
Subject: Contralateral lower extremity
Toe pressure
Toe-brachial index
Mortality
Peripheral artery disease
INTER-SOCIETY CONSENSUS
PREDICTS INCREASED RISK
DIGITAL BLOOD-PRESSURE
CARDIOVASCULAR-DISEASE
ISCHEMIC LEG
FOLLOW-UP
DIAGNOSIS
OUTCOMES
RELIABILITY
PREVALENCE
3126 Surgery, anesthesiology, intensive care, radiology
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