Frailty and mortality : an 18-year follow-up study among Finnish community-dwelling older people

Show full item record



Permalink

http://hdl.handle.net/10138/324052

Citation

Salminen , M , Viljanen , A , Eloranta , S , Viikari , P , Wuorela , M , Vahlberg , T , Isoaho , R , Kivelä , S-L , Korhonen , P , Irjala , K , Lopponen , M & Viikari , L 2020 , ' Frailty and mortality : an 18-year follow-up study among Finnish community-dwelling older people ' , Aging Clinical and Experimental Research , vol. 32 , no. 10 , pp. 2013-2019 . https://doi.org/10.1007/s40520-019-01383-4

Title: Frailty and mortality : an 18-year follow-up study among Finnish community-dwelling older people
Author: Salminen, Marika; Viljanen, Anna; Eloranta, Sini; Viikari, Paula; Wuorela, Maarit; Vahlberg, Tero; Isoaho, Raimo; Kivelä, Sirkka-Liisa; Korhonen, Päivi; Irjala, Kerttu; Lopponen, Minna; Viikari, Laura
Contributor: University of Helsinki, Division of Social Pharmacy
Date: 2020-10
Language: eng
Number of pages: 7
Belongs to series: Aging Clinical and Experimental Research
ISSN: 1594-0667
URI: http://hdl.handle.net/10138/324052
Abstract: Background There is a lack of agreement about applicable instrument to screen frailty in clinical settings. Aims To analyze the association between frailty and mortality in Finnish community-dwelling older people. Methods This was a prospective study with 10- and 18-year follow-ups. Frailty was assessed using FRAIL scale (FS) (n = 1152), Rockwood's frailty index (FI) (n = 1126), and PRISMA-7 (n = 1124). To analyze the association between frailty and mortality, Cox regression model was used. Results Prevalence of frailty varied from 2 to 24% based on the index used. In unadjusted models, frailty was associated with higher mortality according to FS (hazard ratio 7.96 [95% confidence interval 5.10-12.41] in 10-year follow-up, and 6.32 [4.17-9.57] in 18-year follow-up) and FI (5.97 [4.13-8.64], and 3.95 [3.16-4.94], respectively) in both follow-ups. Also being pre-frail was associated with higher mortality according to both indexes in both follow-ups (FS 2.19 [1.78-2.69], and 1.69 [1.46-1.96]; FI 1.81[1.25-2.62], and 1.31 [1.07-1.61], respectively). Associations persisted even after adjustments. Also according to PRISMA-7, a binary index (robust or frail), frailty was associated with higher mortality in 10- (4.41 [3.55-5.34]) and 18-year follow-ups (3.78 [3.19-4.49]). Discussion Frailty was associated with higher mortality risk according to all three frailty screening instrument used. Simple and fast frailty indexes, FS and PRISMA-7, seemed to be comparable with a multidimensional time-consuming FI in predicting mortality among community-dwelling Finnish older people. Conclusions FS and PRISMA-7 are applicable frailty screening instruments in clinical setting among community-dwelling Finnish older people.
Subject: Association
Frailty
Mortality
Older people
PRIMARY-HEALTH-CARE
SEX-DIFFERENCES
ADULTS
INSTRUMENTS
VALIDATION
DISABILITY
PHENOTYPE
CONSENSUS
ACCURACY
OUTCOMES
3141 Health care science
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
Salminen2020_Ar ... ndMortalityAn18_yearFo.pdf 665.3Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record