Electronic Cigarettes and Head and Neck Cancer Risk-Current State of Art

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Szukalska , M , Szyfter , K , Florek , E , Rodrigo , J P , Rinaldo , A , Mäkitie , A A , Strojan , P , Takes , R P , Suarez , C , Saba , N F , Braakhuis , B J M & Ferlito , A 2020 , ' Electronic Cigarettes and Head and Neck Cancer Risk-Current State of Art ' , Cancers , vol. 12 , no. 11 , 3274 . https://doi.org/10.3390/cancers12113274

Title: Electronic Cigarettes and Head and Neck Cancer Risk-Current State of Art
Author: Szukalska, Marta; Szyfter, Krzysztof; Florek, Ewa; Rodrigo, Juan P.; Rinaldo, Alessandra; Mäkitie, Antti A.; Strojan, Primoz; Takes, Robert P.; Suarez, Carlos; Saba, Nabil F.; Braakhuis, Boudewijn J. M.; Ferlito, Alfio
Contributor: University of Helsinki, HUS Head and Neck Center
Date: 2020-11
Language: eng
Number of pages: 16
Belongs to series: Cancers
ISSN: 2072-6694
URI: http://hdl.handle.net/10138/324095
Abstract: Simple Summary The risk of developing cancer is always higher for tobacco smokers than for non-smokers. Electronic cigarettes (e-cigarettes) have become increasingly popular in the last decade and are considered less harmful than traditional tobacco products, due to the lower content of toxic and carcinogenic compounds. However, this is still a controversial issue. This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer (HNC). The authors reviewed articles on both toxic and carcinogenic compounds contained in e-cigarettes and their molecular and health effects on the upper respiratory tract in comparison to traditional tobacco cigarettes. In conclusion, the studies discussed in the review strongly suggest that more long-term studies are needed to better address the safety of e-cigarettes. E-cigarettes have become increasingly popular in the last decade and are considered less harmful than traditional tobacco products due to the lower content of toxic and carcinogenic compounds. However, this is still a controversial issue. This paper contains a review of previous reports on the composition of e-cigarettes and their impact on the pathogenesis and risk of head and neck cancer (HNC). The objective of the review was to compare the molecular and health effects of e-cigarette use in relation to the effects of traditional cigarette smoking in the upper respiratory tract, and to assess the safety and effect of e-cigarettes on HNC risk. A review for English language articles published until 31 August 2020 was made, using a PubMed (including MEDLINE), CINAHL Plus, Embase, Cochrane Library and Web of Science data. The authors reviewed articles on both toxic and carcinogenic compounds contained in e-cigarettes and their molecular and health effects on the upper respiratory tract in comparison to tobacco cigarettes. The risk of developing head and neck squamous cell carcinoma (HNSCC) remains lower in users of e-cigarettes compared with tobacco smokers. However, more long-term studies are needed to better address the safety of e-cigarettes.
Subject: electronic cigarettes
toxicity
carcinogenic compounds
head and neck cancer
head and neck squamous cell carcinoma
REPLACEMENT LIQUIDS
GAS-CHROMATOGRAPHY
MUCOSAL TISSUE
NICOTINE
EXPOSURE
CYTOTOXICITY
SMOKERS
AEROSOL
SYSTEM
FLUIDS
3122 Cancers
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