Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study

Näytä kaikki kuvailutiedot



Pysyväisosoite

http://hdl.handle.net/10138/324644

Lähdeviite

GlobalSurg Collaborative , Drake , T M , Tolonen , M , Leppäniemi , A , Sallinen , V & Sund , M 2020 , ' Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study ' , BMJ global health , vol. 5 , no. 12 , 003429 . https://doi.org/10.1136/bmjgh-2020-003429

Julkaisun nimi: Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study
Tekijä: GlobalSurg Collaborative; Drake, Thomas M.; Tolonen, Matti; Leppäniemi, Ari; Sallinen, Ville; Sund, Malin
Tekijän organisaatio: HUS Abdominal Center
II kirurgian klinikka
Department of Anatomy
Pertti Panula / Principal Investigator
Clinicum
Päiväys: 2020
Kieli: eng
Sivumäärä: 14
Kuuluu julkaisusarjaan: BMJ global health
ISSN: 2059-7908
DOI-tunniste: https://doi.org/10.1136/bmjgh-2020-003429
URI: http://hdl.handle.net/10138/324644
Tiivistelmä: Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45 center dot 1%) children were from high HDI, 397 (34 center dot 2%) from middle HDI and 239 (20 center dot 6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12 center dot 8% (51/397) in middle HDI and 24 center dot 7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.
Avainsanat: gastro-enterologic surgery
paediatrics
CARE-ASSOCIATED INFECTION
MIDDLE-INCOME COUNTRIES
CONGENITAL-ANOMALIES
GLOBAL BURDEN
AFRICA
3142 Public health care science, environmental and occupational health
3126 Surgery, anesthesiology, intensive care, radiology
Vertaisarvioitu: Kyllä
Tekijänoikeustiedot: cc_by
Pääsyrajoitteet: openAccess
Rinnakkaistallennettu versio: publishedVersion


Tiedostot

Latausmäärä yhteensä: Ladataan...

Tiedosto(t) Koko Formaatti Näytä
e003429.full.pdf 706.0KB PDF Avaa tiedosto

Viite kuuluu kokoelmiin:

Näytä kaikki kuvailutiedot