Moderate alcohol use is associated with decreased brain volume in early middle age in both sexes

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http://hdl.handle.net/10138/324794

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Immonen , S , Launes , J , Järvinen , I , Virta , M , Vanninen , R , Schiavone , N , Lehto , E , Tuulio-Henriksson , A , Lipsanen , J , Michelsson , K & Hokkanen , L 2020 , ' Moderate alcohol use is associated with decreased brain volume in early middle age in both sexes ' , Scientific Reports , vol. 10 , no. 1 , 13998 . https://doi.org/10.1038/s41598-020-70910-5

Title: Moderate alcohol use is associated with decreased brain volume in early middle age in both sexes
Author: Immonen, Satu; Launes, Jyrki; Järvinen, Ilkka; Virta, Maarit; Vanninen, Ritva; Schiavone, Nella; Lehto, Eliisa; Tuulio-Henriksson, Annamari; Lipsanen, Jari; Michelsson, Katarina; Hokkanen, Laura
Contributor: University of Helsinki, Doctoral Programme Brain & Mind
University of Helsinki, Clinicum
University of Helsinki, Medicum
University of Helsinki, Medicum
University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, Department of Psychology and Logopedics
Date: 2020-08-19
Language: eng
Number of pages: 8
Belongs to series: Scientific Reports
ISSN: 2045-2322
URI: http://hdl.handle.net/10138/324794
Abstract: The aim was to examine cross-sectional association between moderate alcohol consumption and total brain volume in a cohort of participants in early middle-age, unconfounded by age-related neuronal change. 353 participants aged 39 to 45 years reported on their alcohol consumption using the AUDIT-C measure. Participants with alcohol abuse were excluded. Brain MRI was analyzed using a fully automated method. Brain volumes were adjusted by intracranial volume expressed as adjusted total brain volume (aTBV). AUDIT-C mean of 3.92 (SD 2.04) indicated moderate consumption. In a linear regression model, alcohol consumption was associated with smaller aTBV (B=- 0.258, p
Subject: AUDIT-C
CONSUMPTION
POPULATION
ADULTS
DRINKING
SAMPLE
RISK
Psykologia
Neuropsykologia
3124 Neurology and psychiatry
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