Roadmap for a precision-medicine initiative in the Nordic region

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Njolstad , P R , Andreassen , O A , Brunak , S , Borglum , A D , Dillner , J , Esko , T , Franks , P W , Freimer , N , Groop , L , Heimer , H , Hougaard , D M , Hovig , E , Hveem , K , Jalanko , A , Kaprio , J , Knudsen , G P , Melbye , M , Metspalu , A , Mortensen , P B , Palmgren , J , Palotie , A , Reed , W , Stefansson , H , Stitziel , N O , Sullivan , P F , Thorsteinsdottir , U , Vaudel , M , Vuorio , E , Werge , T , Stoltenberg , C & Stefansson , K 2019 , ' Roadmap for a precision-medicine initiative in the Nordic region ' , Nature Genetics , vol. 51 , no. 6 , pp. 924-930 . https://doi.org/10.1038/s41588-019-0391-1

Title: Roadmap for a precision-medicine initiative in the Nordic region
Author: Njolstad, Pal Rasmus; Andreassen, Ole Andreas; Brunak, Soren; Borglum, Anders D.; Dillner, Joakim; Esko, Tonu; Franks, Paul W.; Freimer, Nelson; Groop, Leif; Heimer, Hakon; Hougaard, David M.; Hovig, Eivind; Hveem, Kristian; Jalanko, Anu; Kaprio, Jaakko; Knudsen, Gun Peggy; Melbye, Mads; Metspalu, Andres; Mortensen, Preben Bo; Palmgren, Juni; Palotie, Aarno; Reed, Wenche; Stefansson, Hreinn; Stitziel, Nathan O.; Sullivan, Patrick F.; Thorsteinsdottir, Unnur; Vaudel, Marc; Vuorio, Eero; Werge, Thomas; Stoltenberg, Camilla; Stefansson, Kari
Contributor: University of Helsinki, Centre of Excellence in Complex Disease Genetics
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Centre of Excellence in Complex Disease Genetics
Date: 2019-06
Language: eng
Number of pages: 7
Belongs to series: Nature Genetics
ISSN: 1061-4036
URI: http://hdl.handle.net/10138/325612
Abstract: The Nordic region, comprising primarily Denmark, Estonia, Finland, Iceland, Norway and Sweden, has many of the necessary characteristics for being at the forefront of genome-based precision medicine. These include egalitarian and universal healthcare, expertly curated patient and population registries, biobanks, large population-based prospective cohorts linked to registries and biobanks, and a widely embraced sense of social responsibility that motivates public engagement in biomedical research. However, genome-based precision medicine can be achieved only through coordinated action involving all actors in the healthcare sector. Now is an opportune time to organize scientists in the Nordic region, together with other stakeholders including patient representatives, governments, pharmaceutical companies, academic institutions and funding agencies, to initiate a Nordic Precision Medicine Initiative. We present a roadmap for how this organization can be created. The Initiative should facilitate research, clinical trials and knowledge transfer to meet regional and global health challenges.
Subject: SINGLE BRCA2 MUTATION
FREQUENCY
1184 Genetics, developmental biology, physiology
3111 Biomedicine
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