Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes

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Hess , S , Kneis , D , Osterlund , T , Li , B , Kristiansson , E & Berendonk , T U 2019 , ' Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes ' , Environmental Science & Technology , vol. 53 , no. 23 , pp. 13898-13905 . https://doi.org/10.1021/acs.est.9b03236

Title: Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes
Author: Hess, Stefanie; Kneis, David; Osterlund, Tobias; Li, Bing; Kristiansson, Erik; Berendonk, Thomas U.
Contributor: University of Helsinki, Department of Microbiology
Date: 2019-12-03
Language: eng
Number of pages: 8
Belongs to series: Environmental Science & Technology
ISSN: 0013-936X
URI: http://hdl.handle.net/10138/326230
Abstract: Airplane sanitary facilities are shared by an international audience. We hypothesized the corresponding sewage to be an extraordinary source of antibiotic-resistant bacteria (ARB) and resistance genes (ARG) in terms of diversity and quantity. Accordingly, we analyzed ARG and ARB in airplane-borne sewage using complementary approaches: metagenomics, quantitative polymerase chain reaction (qPCR), and cultivation. For the purpose of comparison, we also quantified ARG and ARB in the inlets of municipal treatment plants with and without connection to airports. As expected, airplane sewage contained an extraordinarily rich set of mobile ARG, and the relative abundances of genes were mostly increased compared to typical raw sewage of municipal origin. Moreover, combined resistance against third-generation cephalosporins, fluorochinolones, and aminoglycosides was unusually common (28.9%) among Escherichia coli isolated from airplane sewage. This percentage exceeds the one reported for German clinical isolates by a factor of 8. Our findings suggest that airplane-borne sewage can effectively contribute to the fast and global spread of antibiotic resistance.
Subject: RIBOSOMAL-RNA
WATER
IDENTIFICATION
1172 Environmental sciences
1181 Ecology, evolutionary biology
1183 Plant biology, microbiology, virology
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