Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes

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Pysyväisosoite

http://hdl.handle.net/10138/326230

Lähdeviite

Hess , S , Kneis , D , Osterlund , T , Li , B , Kristiansson , E & Berendonk , T U 2019 , ' Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes ' , Environmental Science & Technology , vol. 53 , no. 23 , pp. 13898-13905 . https://doi.org/10.1021/acs.est.9b03236

Julkaisun nimi: Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes
Tekijä: Hess, Stefanie; Kneis, David; Osterlund, Tobias; Li, Bing; Kristiansson, Erik; Berendonk, Thomas U.
Tekijän organisaatio: Department of Microbiology
Päiväys: 2019-12-03
Kieli: eng
Sivumäärä: 8
Kuuluu julkaisusarjaan: Environmental Science & Technology
ISSN: 0013-936X
DOI-tunniste: https://doi.org/10.1021/acs.est.9b03236
URI: http://hdl.handle.net/10138/326230
Tiivistelmä: Airplane sanitary facilities are shared by an international audience. We hypothesized the corresponding sewage to be an extraordinary source of antibiotic-resistant bacteria (ARB) and resistance genes (ARG) in terms of diversity and quantity. Accordingly, we analyzed ARG and ARB in airplane-borne sewage using complementary approaches: metagenomics, quantitative polymerase chain reaction (qPCR), and cultivation. For the purpose of comparison, we also quantified ARG and ARB in the inlets of municipal treatment plants with and without connection to airports. As expected, airplane sewage contained an extraordinarily rich set of mobile ARG, and the relative abundances of genes were mostly increased compared to typical raw sewage of municipal origin. Moreover, combined resistance against third-generation cephalosporins, fluorochinolones, and aminoglycosides was unusually common (28.9%) among Escherichia coli isolated from airplane sewage. This percentage exceeds the one reported for German clinical isolates by a factor of 8. Our findings suggest that airplane-borne sewage can effectively contribute to the fast and global spread of antibiotic resistance.
Avainsanat: RIBOSOMAL-RNA
WATER
IDENTIFICATION
1172 Environmental sciences
1181 Ecology, evolutionary biology
1183 Plant biology, microbiology, virology
Vertaisarvioitu: Kyllä
Tekijänoikeustiedot: unspecified
Pääsyrajoitteet: openAccess
Rinnakkaistallennettu versio: acceptedVersion


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