Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes

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dc.contributor.author Hess, Stefanie
dc.contributor.author Kneis, David
dc.contributor.author Osterlund, Tobias
dc.contributor.author Li, Bing
dc.contributor.author Kristiansson, Erik
dc.contributor.author Berendonk, Thomas U.
dc.date.accessioned 2021-02-09T13:55:01Z
dc.date.available 2021-02-09T13:55:01Z
dc.date.issued 2019-12-03
dc.identifier.citation Hess , S , Kneis , D , Osterlund , T , Li , B , Kristiansson , E & Berendonk , T U 2019 , ' Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes ' , Environmental Science & Technology , vol. 53 , no. 23 , pp. 13898-13905 . https://doi.org/10.1021/acs.est.9b03236
dc.identifier.other PURE: 131792782
dc.identifier.other PURE UUID: 1b3cba8e-65f9-41f5-8acd-0fa4459f3524
dc.identifier.other WOS: 000500838900038
dc.identifier.uri http://hdl.handle.net/10138/326230
dc.description.abstract Airplane sanitary facilities are shared by an international audience. We hypothesized the corresponding sewage to be an extraordinary source of antibiotic-resistant bacteria (ARB) and resistance genes (ARG) in terms of diversity and quantity. Accordingly, we analyzed ARG and ARB in airplane-borne sewage using complementary approaches: metagenomics, quantitative polymerase chain reaction (qPCR), and cultivation. For the purpose of comparison, we also quantified ARG and ARB in the inlets of municipal treatment plants with and without connection to airports. As expected, airplane sewage contained an extraordinarily rich set of mobile ARG, and the relative abundances of genes were mostly increased compared to typical raw sewage of municipal origin. Moreover, combined resistance against third-generation cephalosporins, fluorochinolones, and aminoglycosides was unusually common (28.9%) among Escherichia coli isolated from airplane sewage. This percentage exceeds the one reported for German clinical isolates by a factor of 8. Our findings suggest that airplane-borne sewage can effectively contribute to the fast and global spread of antibiotic resistance. en
dc.format.extent 8
dc.language.iso eng
dc.relation.ispartof Environmental Science & Technology
dc.rights unspecified
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject RIBOSOMAL-RNA
dc.subject WATER
dc.subject IDENTIFICATION
dc.subject 1172 Environmental sciences
dc.subject 1181 Ecology, evolutionary biology
dc.subject 1183 Plant biology, microbiology, virology
dc.title Sewage from Airplanes Exhibits High Abundance and Diversity of Antibiotic Resistance Genes en
dc.type Article
dc.contributor.organization Department of Microbiology
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1021/acs.est.9b03236
dc.relation.issn 0013-936X
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion

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