Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis : Parasite Epidemiology and Control

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dc.contributor.author Olsen, A.
dc.contributor.author Berg, R.
dc.contributor.author Tagel, M.
dc.contributor.author Must, K.
dc.contributor.author Deksne, G.
dc.contributor.author Enemark, H.L.
dc.contributor.author Alban, L.
dc.contributor.author Johansen, M.V.
dc.contributor.author Nielsen, H.V.
dc.contributor.author Sandberg, M.
dc.contributor.author Lundén, A.
dc.contributor.author Stensvold, C.R.
dc.contributor.author Pires, S.M.
dc.contributor.author Jokelainen, P.
dc.date.accessioned 2021-02-12T10:23:01Z
dc.date.available 2021-02-12T10:23:01Z
dc.date.issued 2019
dc.identifier.citation Olsen , A , Berg , R , Tagel , M , Must , K , Deksne , G , Enemark , H L , Alban , L , Johansen , M V , Nielsen , H V , Sandberg , M , Lundén , A , Stensvold , C R , Pires , S M & Jokelainen , P 2019 , ' Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis : Parasite Epidemiology and Control ' , Parasite epidemiology and control , vol. 5 , e00100 . https://doi.org/10.1016/j.parepi.2019.e00100
dc.identifier.other PURE: 160303509
dc.identifier.other PURE UUID: 32aae8dc-3046-445d-997b-6ed57028e679
dc.identifier.other RIS: urn:8393EB490444E831D2B5FEA8B17C2471
dc.identifier.other Scopus: 85062647036
dc.identifier.other ORCID: /0000-0002-3035-5094/work/88674845
dc.identifier.other WOS: 000660067300012
dc.identifier.uri http://hdl.handle.net/10138/326393
dc.description.abstract Background: Toxoplasma gondii is an important foodborne zoonotic parasite. Meat of infected animals is presumed to constitute a major source of human infection and may be a driver of geographical variation in the prevalence of anti-T. gondii antibodies in humans, which is substantial in the Nordic-Baltic region in northern Europe. However, data on seroprevalence of T. gondii in different animal species used for human consumption are scattered. Methods: We conducted a systematic review of seroprevalence studies and meta-analysis to estimate the seroprevalence of T. gondii in five animal species that are raised or hunted for human consumption in the Nordic-Baltic region: domestic pigs (Sus scrofa domesticus), sheep (Ovis aries), cattle (Bos taurus), wild boars (Sus scrofa), and moose (Alces alces). We searched for studies that were conducted between January 1990 and June 2018, and reported in articles, theses, conference abstracts and proceedings, and manuscripts. Subgroup analyses were performed to identify variables influencing the seroprevalence. Findings: From a total of 271 studies identified in the systematic review, 32 were included in the meta-analysis. These comprised of 13 studies on domestic pigs, six on sheep, three on cattle, six on wild boars, and four on moose. The estimated pooled seroprevalence of T. gondii was 6% in domestic pigs (CI 95% : 3–10%), 23% in sheep (CI 95% : 12–36%), 7% in cattle (CI 95% : 1–21%), 33% in wild boars (CI 95% : 26–41%), and 16% in moose (CI 95% : 10–23%). High heterogeneity was observed in the seroprevalence data within each species. In all host species except wild boars, the pooled seroprevalence estimates were significantly higher in animals >1 year of age than in younger animals. Not all studies provided information on animal age, sensitivity and specificity of the serological method employed, and the cut-off values used for defining an animal seropositive. Conclusions: A substantial proportion of animals raised or hunted for human consumption in the region had tested positive for T. gondii. This indicates widespread exposure to T. gondii among animals raised or hunted for human consumption in the region. Large variations were observed in the seroprevalence estimates between the studies in the region; however, studies were too few to identify spatial patterns at country-level. © 2019 en
dc.language.iso eng
dc.relation.ispartof Parasite epidemiology and control
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Europe
dc.subject Food-borne
dc.subject Meat-borne
dc.subject Seroepidemiology
dc.subject Toxoplasmosis
dc.subject Zoonosis
dc.subject age
dc.subject agglutination test
dc.subject complement fixation test
dc.subject domestic pig
dc.subject domestic sheep
dc.subject enzyme linked immunosorbent assay
dc.subject European wild boar
dc.subject latex agglutination test
dc.subject moose
dc.subject nonhuman
dc.subject Review
dc.subject sensitivity and specificity
dc.subject seroprevalence
dc.subject systematic review
dc.subject taurine cattle
dc.subject Toxoplasma gondii
dc.subject 413 Veterinary science
dc.title Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis : Parasite Epidemiology and Control en
dc.type Review Article
dc.contributor.organization Departments of Faculty of Veterinary Medicine
dc.contributor.organization Veterinary Pathology and Parasitology
dc.contributor.organization Veterinary Biosciences
dc.contributor.organization Antti Sukura / Principal Investigator
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.parepi.2019.e00100
dc.relation.issn 2405-6731
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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