Stability and Photoisomerization of Stilbenes Isolated from the Bark of Norway Spruce Roots

Show full item record



Permalink

http://hdl.handle.net/10138/327155

Citation

Latva-Mäenpää, H.; Wufu, R.; Mulat, D.; Sarjala, T.; Saranpää, P.; Wähälä, K. Stability and Photoisomerization of Stilbenes Isolated from the Bark of Norway Spruce Roots. Molecules 2021, 26, 1036.

Title: Stability and Photoisomerization of Stilbenes Isolated from the Bark of Norway Spruce Roots
Author: Latva-Mäenpää, Harri; Wufu, Riziwanguli; Mulat, Daniel; Sarjala, Tytti; Saranpää, Pekka; Wähälä, Kristiina
Publisher: Multidisciplinary Digital Publishing Institute
Date: 2021-02-16
URI: http://hdl.handle.net/10138/327155
Abstract: Stilbenes or stilbenoids, major polyphenolic compounds of the bark of Norway spruce (<i>Picea abies</i> L. Karst), have potential future applications as drugs, preservatives and other functional ingredients due to their antioxidative, antibacterial and antifungal properties. Stilbenes are photosensitive and UV and fluorescent light induce <i>trans</i> to <i>cis</i> isomerisation via intramolecular cyclization. So far, the characterizations of possible new compounds derived from <i>trans</i>-stilbenes under UV light exposure have been mainly tentative based only on UV or MS spectra without utilizing more detailed structural spectroscopy techniques such as NMR. The objective of this work was to study the stability of biologically interesting and readily available stilbenes such as astringin and isorhapontin and their aglucones piceatannol and isorhapontigenin, which have not been studied previously. The effects of fluorescent and UV light and storage on the stability of <i>trans</i> stilbenes were assessed and the identification and characterisation of new compounds formed during our experiments were carried out by chromatographic (HPLC, GC) and spectroscopic techniques (UV, MS, NMR). The stilbenes undergo a <i>trans</i> to <i>cis</i> isomerisation under extended UV irradiation by intramolecular cyclisation (by the formation of a new C-C bond and the loss of two hydrogens) to phenanthrene structures. The characterised compounds are novel and not described previously.


Files in this item

Total number of downloads: Loading...

Files Size Format View
molecules-26-01036-v2.pdf 3.021Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record