Are Older People Aware of Potential Risks Related to Benzodiazepines They are Taking and Has Anything Changed in Risk Awareness Over Ten Years?

Show simple item record

dc.contributor.author Celikkayalar, Ercan
dc.contributor.author Airaksinen, Marja
dc.contributor.author Kivelä, Sirkka-Liisa
dc.contributor.author Nieminen, Jenni
dc.contributor.author Kleme, Jenni
dc.contributor.author Puustinen, Juha
dc.date.accessioned 2021-03-11T13:25:00Z
dc.date.available 2021-03-11T13:25:00Z
dc.date.issued 2021
dc.identifier.citation Celikkayalar , E , Airaksinen , M , Kivelä , S-L , Nieminen , J , Kleme , J & Puustinen , J 2021 , ' Are Older People Aware of Potential Risks Related to Benzodiazepines They are Taking and Has Anything Changed in Risk Awareness Over Ten Years? ' , Patient preference and adherence , vol. 15 , pp. 141-147 . https://doi.org/10.2147/PPA.S280503
dc.identifier.other PURE: 161096895
dc.identifier.other PURE UUID: 1ae437ff-4c7d-493a-84fc-c7752e67a27a
dc.identifier.other WOS: 000614290000001
dc.identifier.uri http://hdl.handle.net/10138/327841
dc.description.abstract Purpose: The use of benzodiazepines and related drugs (BZD) is common among older adults although there is growing evidence of their harmful effects. This study investigated how well older people are aware of the potential risks related to the BZD they are taking and whether the risk awareness has changed in the years between 2004 and 2015. Patients and Methods: The data were collected by interviewing BZD using home-dwelling patients aged >= 65 years with normal cognitive function (MMSE >= 20) who were admitted to the hospital within a 1 month study period in the years 2004 and 2015. Patients were asked whether they were aware of the ten main potential risks related to BZD use. A risk awareness score (range 0-10) was assessed for each patient, each known potential risk yielding one point. Results: The study included 37 patients in 2004 and 31 patients in 2015. In 2004,6/37 patients (16%), while 16/31 patients (52%) in 2015 had risk awareness scores between 6 and 10. Awareness of dependence (p=0.047), interaction with alcohol (p=0.001), dizziness (p=0.002) and developing tolerance (p=0.002) had improved, while awareness of the other potential risks remained unchanged, muscle weakness being the least known (3/37 in 2004 and 4/31 in 2015 were aware of it as a potential risk). Regular BZD use had declined (p=0.043) but pro re nata (PRN; when required) BZD use had increased (p=0.003) between the years 2004 and 2015. Conclusion: Older BZD users' awareness of some potential risks related to BZD use (dependence, interaction with alcohol, dizziness and developing tolerance) had improved between 2004 and 2015, while awareness of other potential risks remained unchanged. en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof Patient preference and adherence
dc.rights cc_by_nc
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject benzodiazepines
dc.subject risk awareness
dc.subject potentially inappropriate medications
dc.subject insomnia
dc.subject aged
dc.subject interview
dc.subject Z-DRUGS
dc.subject INSOMNIA
dc.subject HYPNOTICS
dc.subject EXPERIENCES
dc.subject MEDICATION
dc.subject WITHDRAWAL
dc.subject DECREASES
dc.subject MELATONIN
dc.subject SLEEP
dc.subject USERS
dc.subject 317 Pharmacy
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Are Older People Aware of Potential Risks Related to Benzodiazepines They are Taking and Has Anything Changed in Risk Awareness Over Ten Years? en
dc.type Article
dc.contributor.organization Division of Pharmacology and Pharmacotherapy
dc.contributor.organization Clin­ical Phar­macy Group
dc.contributor.organization Drug Research Program
dc.contributor.organization Helsinki One Health (HOH)
dc.contributor.organization Divisions of Faculty of Pharmacy
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.2147/PPA.S280503
dc.relation.issn 1177-889X
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

Files in this item

Total number of downloads: Loading...

Files Size Format View
ppa_280503_are_ ... sks_related_to_benzodi.pdf 387.2Kb PDF View/Open

This item appears in the following Collection(s)

Show simple item record