Trends in the Management of Non-Vestibular Skull Base and Intracranial Schwannomas

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http://hdl.handle.net/10138/328373

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Suarez , C , Lopez , F , Mendenhall , W M , Andreasen , S , Mikkelsen , L H , Langendijk , J A , Bondi , S , Rodrigo , J P , Bäck , L , Mäkitie , A A , Fernandez-Alvarez , V , Coca-Pelaz , A , Smee , R , Rinaldo , A & Ferlito , A 2021 , ' Trends in the Management of Non-Vestibular Skull Base and Intracranial Schwannomas ' , Cancer management and research , vol. 13 , pp. 463-478 . https://doi.org/10.2147/CMAR.S287410

Title: Trends in the Management of Non-Vestibular Skull Base and Intracranial Schwannomas
Author: Suarez, Carlos; Lopez, Fernando; Mendenhall, William M.; Andreasen, Simon; Mikkelsen, Lauge Hjorth; Langendijk, Johannes A.; Bondi, Stefano; Rodrigo, Juan P.; Bäck, Leif; Mäkitie, Antti A.; Fernandez-Alvarez, Veronica; Coca-Pelaz, Andres; Smee, Robert; Rinaldo, Alessandra; Ferlito, Alfio
Other contributor: University of Helsinki, HUS Head and Neck Center
University of Helsinki, HUS Head and Neck Center







Date: 2021
Language: eng
Number of pages: 16
Belongs to series: Cancer management and research
ISSN: 1179-1322
DOI: https://doi.org/10.2147/CMAR.S287410
URI: http://hdl.handle.net/10138/328373
Abstract: The aim of this review is to analyze the latest trends in the management of nonvestibular skull base and intracranial schwannomas in order to optimize tumor control and quality of life. Non-vestibular cranial nerve schwannomas are rare lesions, representing 5-10% of cranial nerve schwannomas. Management decisions should be individualized depending on tumor size, location and associated functional deficits. Generally, large sized schwannomas exerting significant mass effect with increased intracranial pressure are treated surgically. In some cases, even after optimal skull base resection, it is not possible to achieve a gross total resection because tumor location and extent and/or to reduce morbidity. Thus, subtotal resection followed by stereotactic radiosurgery or fractioned radiotherapy offers an alternative approach. In certain cases, stereotactic radiosurgery or radiotherapy alone achieves good tumor control rates and less morbidity to gross total resection. Finally, given the slow growth rate of most of these tumors, observation with periodic radiographic follow-up approach is also a reasonable alternative for small tumors with few, if any, symptoms.
Subject: schwannoma
head and neck
cranial nerves
non-vestibular
skull base
GAMMA-KNIFE SURGERY
JUGULAR FORAMEN SCHWANNOMAS
FACIAL-NERVE SCHWANNOMAS
ENDOSCOPIC ENDONASAL APPROACH
INFRATEMPORAL FOSSA APPROACH
TRIGEMINAL-SCHWANNOMAS
SURGICAL-MANAGEMENT
STEREOTACTIC RADIOSURGERY
MICROSURGICAL MANAGEMENT
NECK SCHWANNOMAS
3122 Cancers
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