Scoping Review-The Association between Asthma and Environmental Chemicals

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http://hdl.handle.net/10138/328377

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Mattila , T , Santonen , T , Andersen , H R , Katsonouri , A , Szigeti , T , Uhl , M , Wasowicz , W , Lange , R , Bocca , B , Ruggieri , F , Kolossa-Gehring , M , Sarigiannis , D A & Tolonen , H 2021 , ' Scoping Review-The Association between Asthma and Environmental Chemicals ' , International Journal of Environmental Research and Public Health , vol. 18 , no. 3 , 1323 . https://doi.org/10.3390/ijerph18031323

Titel: Scoping Review-The Association between Asthma and Environmental Chemicals
Författare: Mattila, Tiina; Santonen, Tiina; Andersen, Helle Raun; Katsonouri, Andromachi; Szigeti, Tamas; Uhl, Maria; Wasowicz, Wojciech; Lange, Rosa; Bocca, Beatrice; Ruggieri, Flavia; Kolossa-Gehring, Marike; Sarigiannis, Denis A.; Tolonen, Hanna
Upphovmannens organisation: HUS Heart and Lung Center
Keuhkosairauksien yksikkö
Helsinki University Hospital Area
University of Helsinki
Datum: 2021-02
Språk: eng
Sidantal: 13
Tillhör serie: International Journal of Environmental Research and Public Health
ISSN: 1661-7827
DOI: https://doi.org/10.3390/ijerph18031323
Permanenta länken (URI): http://hdl.handle.net/10138/328377
Abstrakt: Asthma is one of the most common chronic diseases worldwide affecting all age groups from children to the elderly. In addition to other factors such as smoking, air pollution and atopy, some environmental chemicals are shown or suspected to increase the risk of asthma, exacerbate asthma symptoms and cause other respiratory symptoms. In this scoping review, we report environmental chemicals, prioritized for investigation in the European Human Biomonitoring Initiative (HBM4EU), which are associated or possibly associated with asthma. The substance groups considered to cause asthma through specific sensitization include: diisocyanates, hexavalent chromium Cr(VI) and possibly p-phenylenediamine (p-PDA). In epidemiological studies, polyaromatic hydrocarbons (PAHs) and organophosphate insecticides are associated with asthma, and phthalates, per- and polyfluoroalkyl substances (PFASs), pyrethroid insecticides, mercury, cadmium, arsenic and lead are only potentially associated with asthma. As a conclusion, exposure to PAHs and some pesticides are associated with increased risk of asthma. Diisocyanates and Cr(VI) cause asthma with specific sensitization. For many environmental chemicals, current studies have provided contradicting results in relation to increased risk of asthma. Therefore, more research about exposure to environmental chemicals and risk of asthma is needed.
Subject: asthma
environmental chemicals
exposure
HBM4EU
occupation
3142 Public health care science, environmental and occupational health
Referentgranskad: Ja
Licens: cc_by
Användningsbegränsning: openAccess
Parallelpublicerad version: publishedVersion


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