Scoping Review-The Association between Asthma and Environmental Chemicals

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dc.contributor.author Mattila, Tiina
dc.contributor.author Santonen, Tiina
dc.contributor.author Andersen, Helle Raun
dc.contributor.author Katsonouri, Andromachi
dc.contributor.author Szigeti, Tamas
dc.contributor.author Uhl, Maria
dc.contributor.author Wasowicz, Wojciech
dc.contributor.author Lange, Rosa
dc.contributor.author Bocca, Beatrice
dc.contributor.author Ruggieri, Flavia
dc.contributor.author Kolossa-Gehring, Marike
dc.contributor.author Sarigiannis, Denis A.
dc.contributor.author Tolonen, Hanna
dc.date.accessioned 2021-03-26T05:21:02Z
dc.date.available 2021-03-26T05:21:02Z
dc.date.issued 2021-02
dc.identifier.citation Mattila , T , Santonen , T , Andersen , H R , Katsonouri , A , Szigeti , T , Uhl , M , Wasowicz , W , Lange , R , Bocca , B , Ruggieri , F , Kolossa-Gehring , M , Sarigiannis , D A & Tolonen , H 2021 , ' Scoping Review-The Association between Asthma and Environmental Chemicals ' , International Journal of Environmental Research and Public Health , vol. 18 , no. 3 , 1323 . https://doi.org/10.3390/ijerph18031323
dc.identifier.other PURE: 161526666
dc.identifier.other PURE UUID: 2c571f07-a045-491f-a988-da3119c4969c
dc.identifier.other WOS: 000615167800001
dc.identifier.other ORCID: /0000-0001-8466-985X/work/91249873
dc.identifier.uri http://hdl.handle.net/10138/328377
dc.description.abstract Asthma is one of the most common chronic diseases worldwide affecting all age groups from children to the elderly. In addition to other factors such as smoking, air pollution and atopy, some environmental chemicals are shown or suspected to increase the risk of asthma, exacerbate asthma symptoms and cause other respiratory symptoms. In this scoping review, we report environmental chemicals, prioritized for investigation in the European Human Biomonitoring Initiative (HBM4EU), which are associated or possibly associated with asthma. The substance groups considered to cause asthma through specific sensitization include: diisocyanates, hexavalent chromium Cr(VI) and possibly p-phenylenediamine (p-PDA). In epidemiological studies, polyaromatic hydrocarbons (PAHs) and organophosphate insecticides are associated with asthma, and phthalates, per- and polyfluoroalkyl substances (PFASs), pyrethroid insecticides, mercury, cadmium, arsenic and lead are only potentially associated with asthma. As a conclusion, exposure to PAHs and some pesticides are associated with increased risk of asthma. Diisocyanates and Cr(VI) cause asthma with specific sensitization. For many environmental chemicals, current studies have provided contradicting results in relation to increased risk of asthma. Therefore, more research about exposure to environmental chemicals and risk of asthma is needed. en
dc.format.extent 13
dc.language.iso eng
dc.relation.ispartof International Journal of Environmental Research and Public Health
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject asthma
dc.subject environmental chemicals
dc.subject exposure
dc.subject HBM4EU
dc.subject occupation
dc.subject 3142 Public health care science, environmental and occupational health
dc.title Scoping Review-The Association between Asthma and Environmental Chemicals en
dc.type Review Article
dc.contributor.organization HUS Heart and Lung Center
dc.contributor.organization Keuhkosairauksien yksikkö
dc.contributor.organization Helsinki University Hospital Area
dc.contributor.organization University of Helsinki
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.3390/ijerph18031323
dc.relation.issn 1661-7827
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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