Population transcriptomics reveals weak parallel genetic basis in repeated marine and freshwater divergence in nine-spined sticklebacks

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http://hdl.handle.net/10138/328958

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Wang , Y , Zhao , Y , Wang , Y , Li , Z , Guo , B & Merilä , J 2020 , ' Population transcriptomics reveals weak parallel genetic basis in repeated marine and freshwater divergence in nine-spined sticklebacks ' , Molecular Ecology , vol. 29 , no. 9 , pp. 1642-1656 . https://doi.org/10.1111/mec.15435

Title: Population transcriptomics reveals weak parallel genetic basis in repeated marine and freshwater divergence in nine-spined sticklebacks
Author: Wang, Yingnan; Zhao, Yongxin; Wang, Yu; Li, Zitong; Guo, Baocheng; Merilä, Juha
Contributor organization: Ecological Genetics Research Unit
Organismal and Evolutionary Biology Research Programme
Date: 2020-05
Language: eng
Number of pages: 15
Belongs to series: Molecular Ecology
ISSN: 0962-1083
DOI: https://doi.org/10.1111/mec.15435
URI: http://hdl.handle.net/10138/328958
Abstract: Abstract The degree to which adaptation to similar selection pressures is underlain by parallel vs. non-parallel genetic changes is a topic of broad interest in contemporary evolutionary biology. Sticklebacks provide opportunities to characterize and compare the genetic underpinnings of repeated marine-freshwater divergences at both intra- and interspecific levels. While the degree of genetic parallelism in repeated marine-freshwater divergences has been frequently studied in the three-spined stickleback (Gasterosteus aculeatus), much less is known about this in other stickleback species. Using a population transcriptomic approach, we identified both genetic and gene expression variations associated with marine-freshwater divergence in the nine-spined stickleback (Pungitius pungitius). Specifically, we used a genome-wide association study approach, and found that ~1% of the total 173,491 identified SNPs showed marine-freshwater ecotypic differentiation. A total of 861 genes were identified to have SNPs associated with marine-freshwater divergence in nine-spined stickleback, but only 12 of these genes have also been reported as candidates associated with marine-freshwater divergence in the three-spined stickleback. Hence, our results indicate a low degree of interspecific genetic parallelism in marine-freshwater divergence. Moreover, 1,578 genes in the brain and 1,050 genes in the liver were differentially expressed between marine and freshwater nine-spined sticklebacks, ~5% of which have also been identified as candidates associated with marine-freshwater divergence in the three-spined stickleback. However, only few of these (e.g., CLDND1) appear to have been involved in repeated marine-freshwater divergence in nine-spined sticklebacks. Taken together, the results indicate a low degree of genetic parallelism in repeated marine-freshwater divergence both at intra- and interspecific levels.
Subject: 1181 Ecology, evolutionary biology
1184 Genetics, developmental biology, physiology
Expression divergence
Gasterosteidae
Genetic parallelism
RNA-seq
SNP
PELVIC REDUCTION
CONVERGENT EVOLUTION
PUNGITIUS-PUNGITIUS
VARIABLE SELECTION
genetic parallelism
expression divergence
ARCHITECTURE
THREESPINE STICKLEBACK
SALINITY
EXPRESSION
ADAPTIVE EVOLUTION
GENOMIC BASIS
Peer reviewed: Yes
Rights: unspecified
Usage restriction: openAccess
Self-archived version: acceptedVersion


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