Gender differences in screening for glucose perturbations, cardiovascular risk factor management and prognosis in patients with dysglycaemia and coronary artery disease : results from the ESC-EORP EUROASPIRE surveys

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EUROASPIRE IV Investigator , EUROASPIRE V Investigator , Ferrannini , G , De Bacquer , D , Vynckier , P , Tuomilehto , J & Ryden , L 2021 , ' Gender differences in screening for glucose perturbations, cardiovascular risk factor management and prognosis in patients with dysglycaemia and coronary artery disease : results from the ESC-EORP EUROASPIRE surveys ' , Cardiovascular Diabetology , vol. 20 , no. 1 , 38 . https://doi.org/10.1186/s12933-021-01233-6

Title: Gender differences in screening for glucose perturbations, cardiovascular risk factor management and prognosis in patients with dysglycaemia and coronary artery disease : results from the ESC-EORP EUROASPIRE surveys
Author: EUROASPIRE IV Investigator; EUROASPIRE V Investigator; Ferrannini, Giulia; De Bacquer, Dirk; Vynckier, Pieter; Tuomilehto, Jaakko; Ryden, Lars
Contributor organization: Clinicum
Department of Public Health
University of Helsinki
Date: 2021-02-11
Language: eng
Number of pages: 12
Belongs to series: Cardiovascular Diabetology
ISSN: 1475-2840
DOI: https://doi.org/10.1186/s12933-021-01233-6
URI: http://hdl.handle.net/10138/329121
Abstract: BackgroundGender disparities in the management of dysglycaemia, defined as either impaired glucose tolerance (IGT) or type 2 diabetes (T2DM), in coronary artery disease (CAD) patients are a medical challenge. Recent data from two nationwide cohorts of patients suggested no gender difference as regards the risk for diabetes-related CV complications but indicated the presence of a gender disparity in risk factor management. The aim of this study was to investigate gender differences in screening for dysglycaemia, cardiovascular risk factor management and prognosis in dysglycemic CAD patients.MethodsThe study population (n=16,259; 4077 women) included 7998 patients from the ESC-EORP EUROASPIRE IV (EAIV: 2012-2013, 79 centres in 24 countries) and 8261 patients from the ESC-EORP EUROASPIRE V (EAV: 2016-2017, 131 centres in 27 countries) cross-sectional surveys. In each centre, patients were investigated with standardised methods by centrally trained staff and those without known diabetes were offered an oral glucose tolerance test (OGTT). The first of CV death or hospitalisation for non-fatal myocardial infarction, stroke, heart failure or revascularization served as endpoint. Median follow-up time was 1.7 years. The association between gender and time to the occurrence of the endpoint was evaluated using Cox survival modelling, adjusting for age.ResultsKnown diabetes was more common among women (32.9%) than men (28.4%, p
Subject: Diabetes
Coronary artery disease
Gender
Impaired glucose tolerance
Prevention
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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