Gender differences in screening for glucose perturbations, cardiovascular risk factor management and prognosis in patients with dysglycaemia and coronary artery disease : results from the ESC-EORP EUROASPIRE surveys

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dc.contributor.author EUROASPIRE IV Investigator
dc.contributor.author EUROASPIRE V Investigator
dc.contributor.author Ferrannini, Giulia
dc.contributor.author De Bacquer, Dirk
dc.contributor.author Vynckier, Pieter
dc.contributor.author Tuomilehto, Jaakko
dc.contributor.author Ryden, Lars
dc.date.accessioned 2021-04-16T11:44:02Z
dc.date.available 2021-04-16T11:44:02Z
dc.date.issued 2021-02-11
dc.identifier.citation EUROASPIRE IV Investigator , EUROASPIRE V Investigator , Ferrannini , G , De Bacquer , D , Vynckier , P , Tuomilehto , J & Ryden , L 2021 , ' Gender differences in screening for glucose perturbations, cardiovascular risk factor management and prognosis in patients with dysglycaemia and coronary artery disease : results from the ESC-EORP EUROASPIRE surveys ' , Cardiovascular Diabetology , vol. 20 , no. 1 , 38 . https://doi.org/10.1186/s12933-021-01233-6
dc.identifier.other PURE: 162245841
dc.identifier.other PURE UUID: 30bff97c-f8dd-403c-9f63-690c913f116a
dc.identifier.other WOS: 000619710000001
dc.identifier.uri http://hdl.handle.net/10138/329121
dc.description.abstract BackgroundGender disparities in the management of dysglycaemia, defined as either impaired glucose tolerance (IGT) or type 2 diabetes (T2DM), in coronary artery disease (CAD) patients are a medical challenge. Recent data from two nationwide cohorts of patients suggested no gender difference as regards the risk for diabetes-related CV complications but indicated the presence of a gender disparity in risk factor management. The aim of this study was to investigate gender differences in screening for dysglycaemia, cardiovascular risk factor management and prognosis in dysglycemic CAD patients.MethodsThe study population (n=16,259; 4077 women) included 7998 patients from the ESC-EORP EUROASPIRE IV (EAIV: 2012-2013, 79 centres in 24 countries) and 8261 patients from the ESC-EORP EUROASPIRE V (EAV: 2016-2017, 131 centres in 27 countries) cross-sectional surveys. In each centre, patients were investigated with standardised methods by centrally trained staff and those without known diabetes were offered an oral glucose tolerance test (OGTT). The first of CV death or hospitalisation for non-fatal myocardial infarction, stroke, heart failure or revascularization served as endpoint. Median follow-up time was 1.7 years. The association between gender and time to the occurrence of the endpoint was evaluated using Cox survival modelling, adjusting for age.ResultsKnown diabetes was more common among women (32.9%) than men (28.4%, p en
dc.format.extent 12
dc.language.iso eng
dc.relation.ispartof Cardiovascular Diabetology
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Diabetes
dc.subject Coronary artery disease
dc.subject Gender
dc.subject Impaired glucose tolerance
dc.subject Prevention
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Gender differences in screening for glucose perturbations, cardiovascular risk factor management and prognosis in patients with dysglycaemia and coronary artery disease : results from the ESC-EORP EUROASPIRE surveys en
dc.type Article
dc.contributor.organization Clinicum
dc.contributor.organization Department of Public Health
dc.contributor.organization University of Helsinki
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1186/s12933-021-01233-6
dc.relation.issn 1475-2840
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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