Triggering factors in non-traumatic intracerebral hemorrhage

Visa fullständig post



Permalänk

http://hdl.handle.net/10138/330639

Citation

Sallinen , H , Putaala , J & Strbian , D 2020 , ' Triggering factors in non-traumatic intracerebral hemorrhage ' , Journal of Stroke & Cerebrovascular Diseases , vol. 29 , no. 8 , 104921 . https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104921

Titel: Triggering factors in non-traumatic intracerebral hemorrhage
Författare: Sallinen, Hanne; Putaala, Jukka; Strbian, Daniel
Upphovmannens organisation: Neurologian yksikkö
Helsinki University Hospital Area
HUS Neurocenter
University of Helsinki
Department of Neurosciences
Datum: 2020-08
Språk: eng
Sidantal: 7
Tillhör serie: Journal of Stroke & Cerebrovascular Diseases
ISSN: 1052-3057
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104921
Permanenta länken (URI): http://hdl.handle.net/10138/330639
Abstrakt: Background: In ischemic stroke and subarachnoid hemorrhage, there are known preceding triggering events that predispose to the stroke by, for example, abruptly raising blood pressure. We explored, whether triggering events can be identified in non-traumatic intracerebral hemorrhage (ICH). Methods: We used structured questionnaires to interview consented patients with ICH treated in a tertiary teaching hospital, between 2014 and 2016. We asked of possible trigger factors, including Valsalva-inducing activity, heavy physical exertion, sexual activity, abrupt change in position, a heavy meal, a sudden change in temperature, exposure to traffic jam, and the combination of the first three (any physical trigger) during the hazard period of 0-2 h prior to ICH. The ratio of the reported trigger during the hazard period was compared to the same 2-h period the previous day (control period) to calculate the relative risks for each factor (case-crossover design). Results: Of our 216 consented ICH patients, 97 (35.0%) could be interviewed for trigger questions. Reasons for not able to provide consistent and reliable responses included lowered level of consciousness, delirium, impaired memory, and aphasia. None of the studied possible triggers alone were more frequent during the hazard period compared to the control period. However, when all physical triggers were combined, we found an association with the triggering event and onset of ICH (risk ratio 1.32, 95% confidence interval 1.01-1.73). Conclusions: Obtaining reliable information on the preceding events before ICH onset was challenging. However, we found that physical triggers as a group were associated with the onset of ICH.
Subject: Intracerebral hemorrhage
Risk factor
Trigger
Stroke
ACUTE MYOCARDIAL-INFARCTION
HEAVY PHYSICAL EXERTION
CASE-CROSSOVER
RISK-FACTORS
STROKE
POPULATION
EXERCISE
PRESSURE
ONSET
3112 Neurosciences
3124 Neurology and psychiatry
Referentgranskad: Ja
Licens: cc_by_nc_nd
Användningsbegränsning: openAccess
Parallelpublicerad version: acceptedVersion


Filer under denna titel

Totalt antal nerladdningar: Laddar...

Filer Storlek Format Granska
Triggering_factors_in_ICH_revision_clean_copy.pdf 77.93Kb PDF Granska/Öppna

Detta dokument registreras i samling:

Visa fullständig post