Triggering factors in non-traumatic intracerebral hemorrhage

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dc.contributor.author Sallinen, Hanne
dc.contributor.author Putaala, Jukka
dc.contributor.author Strbian, Daniel
dc.date.accessioned 2021-06-04T22:34:08Z
dc.date.available 2021-12-18T03:45:15Z
dc.date.issued 2020-08
dc.identifier.citation Sallinen , H , Putaala , J & Strbian , D 2020 , ' Triggering factors in non-traumatic intracerebral hemorrhage ' , Journal of Stroke & Cerebrovascular Diseases , vol. 29 , no. 8 , 104921 . https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104921
dc.identifier.other PURE: 144690816
dc.identifier.other PURE UUID: c326ea85-b517-4bad-b9a5-4b870a34f1b4
dc.identifier.other WOS: 000561808800059
dc.identifier.uri http://hdl.handle.net/10138/330639
dc.description.abstract Background: In ischemic stroke and subarachnoid hemorrhage, there are known preceding triggering events that predispose to the stroke by, for example, abruptly raising blood pressure. We explored, whether triggering events can be identified in non-traumatic intracerebral hemorrhage (ICH). Methods: We used structured questionnaires to interview consented patients with ICH treated in a tertiary teaching hospital, between 2014 and 2016. We asked of possible trigger factors, including Valsalva-inducing activity, heavy physical exertion, sexual activity, abrupt change in position, a heavy meal, a sudden change in temperature, exposure to traffic jam, and the combination of the first three (any physical trigger) during the hazard period of 0-2 h prior to ICH. The ratio of the reported trigger during the hazard period was compared to the same 2-h period the previous day (control period) to calculate the relative risks for each factor (case-crossover design). Results: Of our 216 consented ICH patients, 97 (35.0%) could be interviewed for trigger questions. Reasons for not able to provide consistent and reliable responses included lowered level of consciousness, delirium, impaired memory, and aphasia. None of the studied possible triggers alone were more frequent during the hazard period compared to the control period. However, when all physical triggers were combined, we found an association with the triggering event and onset of ICH (risk ratio 1.32, 95% confidence interval 1.01-1.73). Conclusions: Obtaining reliable information on the preceding events before ICH onset was challenging. However, we found that physical triggers as a group were associated with the onset of ICH. en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof Journal of Stroke & Cerebrovascular Diseases
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Intracerebral hemorrhage
dc.subject Risk factor
dc.subject Trigger
dc.subject Stroke
dc.subject ACUTE MYOCARDIAL-INFARCTION
dc.subject HEAVY PHYSICAL EXERTION
dc.subject CASE-CROSSOVER
dc.subject RISK-FACTORS
dc.subject STROKE
dc.subject POPULATION
dc.subject EXERCISE
dc.subject PRESSURE
dc.subject ONSET
dc.subject 3112 Neurosciences
dc.subject 3124 Neurology and psychiatry
dc.title Triggering factors in non-traumatic intracerebral hemorrhage en
dc.type Article
dc.contributor.organization Neurologian yksikkö
dc.contributor.organization Helsinki University Hospital Area
dc.contributor.organization HUS Neurocenter
dc.contributor.organization University of Helsinki
dc.contributor.organization Department of Neurosciences
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104921
dc.relation.issn 1052-3057
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion

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