Vitamin C May Increase the Recovery Rate of Outpatient Cases of SARS-CoV-2 Infection by 70%: Reanalysis of the COVID A to Z Randomized Clinical Trial

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Hemilä , H , Carr , A & Chalker , E 2021 , ' Vitamin C May Increase the Recovery Rate of Outpatient Cases of SARS-CoV-2 Infection by 70%: Reanalysis of the COVID A to Z Randomized Clinical Trial ' , Frontiers in Immunology , vol. 12 , 674681 . https://doi.org/10.3389/fimmu.2021.674681

Title: Vitamin C May Increase the Recovery Rate of Outpatient Cases of SARS-CoV-2 Infection by 70%: Reanalysis of the COVID A to Z Randomized Clinical Trial
Author: Hemilä, Harri; Carr, Anitra; Chalker, Elizabeth
Other contributor: University of Helsinki, Clinicum



Date: 2021-05-10
Language: eng
Number of pages: 4
Belongs to series: Frontiers in Immunology
ISSN: 1664-3224
DOI: https://doi.org/10.3389/fimmu.2021.674681
URI: http://hdl.handle.net/10138/331365
Abstract: Given the previous research on vitamin C, we read with great interest the report on the COVID A to Z Randomized Clinical Trial (COVID A to Z trial) which investigated the effects of 8 g/day vitamin C on the recovery from outpatient SARS-CoV-2 infection (9). However, we unfortunately found several methodological shortcomings in the trial. Here we describe our major concerns and statistical reanalysis of the findings.
Subject: 3121 General medicine, internal medicine and other clinical medicine
ascorbic acid
COVID-19
common cold
quantile treatment effect
randomized controlled trials
SARS-CoV-2
statistics
treatment outcome
COMMON COLD
DURATION
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