Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010-2018

Show full item record



Permalink

http://hdl.handle.net/10138/331704

Citation

Möller , V , Östholm-Balkhed , Å , Berild , D , Fredriksson , M , Gottfredsson , M , Holmbom , M , Järvinen , A , Kristjansson , M , Rydell , U , Sonksen , U W , Kolmos , H J & Hanberger , H 2021 , ' Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010-2018 ' , Infectious Diseases , vol. 53 , no. 8 , pp. 607-618 . https://doi.org/10.1080/23744235.2021.1910338

Title: Antibiotic resistance among major pathogens compared to hospital treatment guidelines and antibiotic use in Nordic hospitals 2010-2018
Author: Möller, Vidar; Östholm-Balkhed, Åse; Berild, Dag; Fredriksson, Mats; Gottfredsson, Magnus; Holmbom, Martin; Järvinen, Asko; Kristjansson, Mar; Rydell, Ulf; Sonksen, Ute Wolff; Kolmos, Hans Joern; Hanberger, Håkan
Other contributor: University of Helsinki, HUS Inflammation Center



Date: 2021-08-03
Language: eng
Number of pages: 12
Belongs to series: Infectious Diseases
ISSN: 2374-4235
DOI: https://doi.org/10.1080/23744235.2021.1910338
URI: http://hdl.handle.net/10138/331704
Abstract: Background The Nordic countries have comparable nationwide antibiotic resistance surveillance systems and individual antibiotic stewardship programmes. The aim of this study was to assess antibiotic resistance among major pathogens in relation to practice guidelines for hospital antibiotic treatment and antibiotic use in Nordic countries 2010-2018. Methods Antibiotic resistance among invasive isolates from 2010-2018 and aggregated antibiotic use were obtained from the European Centre for Disease Prevention and Control. Hospital practice guidelines were obtained from national or regional guidelines. Results Antibiotic resistance levels among Escherichia coli and Klebsiella pneumoniae were similar in all Nordic countries in 2018 and low compared to the European mean. Guidelines for acute pyelonephritis varied; 2nd generation cephalosporin (Finland), 3rd generation cephalosporins (Sweden, Norway), ampicillin with an aminoglycoside or aminoglycoside monotherapy (Denmark, Iceland and Norway). Corresponding guidelines for sepsis of unknown origin were 2nd (Finland) or 3rd (Sweden, Norway, Iceland) generation cephalosporins, carbapenems, (Sweden) combinations of penicillin with an aminoglycoside (Norway, Denmark), or piperacillin-tazobactam (all Nordic countries). Methicillin-resistant Staphylococcus aureus rates were 0-2% and empirical treatment with anti-MRSA antibiotics was not recommended in any country. Rates of penicillin non-susceptibility among Streptococcus pneumoniae were low (
Subject: Antibiotic resistance
practice guidelines as topic
antibiotic stewardship
Nordic countries
INVASIVE STREPTOCOCCUS-PNEUMONIAE
SEPTIC SHOCK
ANTIMICROBIAL RESISTANCE
SEPSIS
THERAPY
DEFINITIONS
STEWARDSHIP
BACTEREMIA
CLONALITY
FINLAND
3121 General medicine, internal medicine and other clinical medicine
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
Antibiotic_resi ... ic_hospitals_2010_2018.pdf 2.221Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record