Applications of CRISPR-Cas9 as an Advanced Genome Editing System in Life Sciences

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http://hdl.handle.net/10138/332429

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Tavakoli , K , Pour-Aboughadareh , A , Kianersi , F , Poczai , P , Etminan , A & Shooshtari , L 2021 , ' Applications of CRISPR-Cas9 as an Advanced Genome Editing System in Life Sciences ' , BioTech , vol. 10 , no. 3 , 14 . https://doi.org/10.3390/biotech10030014

Title: Applications of CRISPR-Cas9 as an Advanced Genome Editing System in Life Sciences
Author: Tavakoli, Kamand; Pour-Aboughadareh, Alireza; Kianersi, Farzad; Poczai, Péter; Etminan, Alireza; Shooshtari, Lia
Contributor: University of Helsinki, Botany
Date: 2021
Language: eng
Belongs to series: BioTech
ISSN: 2673-6284
URI: http://hdl.handle.net/10138/332429
Abstract: Targeted nucleases are powerful genomic tools to precisely change the target genome of living cells, controlling functional genes with high exactness. The clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9) genome editing system has been identified as one of the most useful biological tools in genetic engineering that is taken from adaptive immune strategies for bacteria. In recent years, this system has made significant progress and it has been widely used in genome editing to create gene knock-ins, knock-outs, and point mutations. This paper summarizes the application of this system in various biological sciences, including medicine, plant science, and animal breeding.
Subject: 1184 Genetics, developmental biology, physiology
414 Agricultural biotechnology
318 Medical biotechnology
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