Advances in lipidomics

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dc.contributor.author Avela, Henri F.
dc.contributor.author Siren, Heli
dc.date.accessioned 2021-07-16T22:40:33Z
dc.date.available 2021-12-18T03:45:39Z
dc.date.issued 2020-11
dc.identifier.citation Avela , H F & Siren , H 2020 , ' Advances in lipidomics ' , Clinica Chimica Acta , vol. 510 , pp. 123-141 . https://doi.org/10.1016/j.cca.2020.06.049
dc.identifier.other PURE: 156672278
dc.identifier.other PURE UUID: f9699814-2199-41a8-a2c4-7494dc967433
dc.identifier.other WOS: 000582504300022
dc.identifier.uri http://hdl.handle.net/10138/332472
dc.description.abstract The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with multivariate data analysis. This review specifically targets lipid biomarkers and disease pathway mechanisms in humans and artificial targets. Different specimen matrices such as primary blood derivatives (plasma, serum, erythrocytes, and blood platelets), faecal matter, urine, as well as biologic tissues (liver, lung and kidney) are highlighted. en
dc.format.extent 19
dc.language.iso eng
dc.relation.ispartof Clinica Chimica Acta
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Lipids
dc.subject Liquid chromatography
dc.subject Tandem mass spectrometry
dc.subject Clinical profiles
dc.subject Biomarkers
dc.subject Blood
dc.subject PERFORMANCE LIQUID-CHROMATOGRAPHY
dc.subject TANDEM MASS-SPECTROMETRY
dc.subject FIELD-FLOW FRACTIONATION
dc.subject PLATELET-ACTIVATING-FACTOR
dc.subject ESI-QTOF-MS/MS
dc.subject ELECTROSPRAY-IONIZATION
dc.subject LC-MS/MS
dc.subject SAMPLE PREPARATION
dc.subject STRUCTURAL-CHARACTERIZATION
dc.subject POTENTIAL BIOMARKERS
dc.subject 116 Chemical sciences
dc.title Advances in lipidomics en
dc.type Review Article
dc.contributor.organization Department of Chemistry
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.cca.2020.06.049
dc.relation.issn 0009-8981
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion

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