Determination of Phenolic Compounds in Various Propolis Samples Collected from an African and an Asian Region and Their Impact on Antioxidant and Antibacterial Activities

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dc.contributor University of Helsinki, Department of Chemistry en
dc.contributor.author Touzani, Soumaya
dc.contributor.author Imtara, Hamada
dc.contributor.author Katekhaye, Shankar
dc.contributor.author Mechchate, Hamza
dc.contributor.author Ouassou, Hayat
dc.contributor.author Alqahtani, Ali S.
dc.contributor.author Noman, Omar M.
dc.contributor.author Nasr, Fahd A.
dc.contributor.author Fearnley, Hugo
dc.contributor.author Fearnley, James
dc.contributor.author Paradkar, Anant
dc.contributor.author ElArabi, Ilham
dc.contributor.author Lyoussi, Badiaa
dc.date.accessioned 2021-08-20T07:45:01Z
dc.date.available 2021-08-20T07:45:01Z
dc.date.issued 2021-08
dc.identifier.citation Touzani , S , Imtara , H , Katekhaye , S , Mechchate , H , Ouassou , H , Alqahtani , A S , Noman , O M , Nasr , F A , Fearnley , H , Fearnley , J , Paradkar , A , ElArabi , I & Lyoussi , B 2021 , ' Determination of Phenolic Compounds in Various Propolis Samples Collected from an African and an Asian Region and Their Impact on Antioxidant and Antibacterial Activities ' , Molecules , vol. 26 , no. 15 , 4589 . https://doi.org/10.3390/molecules26154589 en
dc.identifier.issn 1420-3049
dc.identifier.other PURE: 167744574
dc.identifier.other PURE UUID: 571269ac-fa55-411b-a78e-4fa845aaacdf
dc.identifier.other WOS: 000682224200001
dc.identifier.uri http://hdl.handle.net/10138/333349
dc.description.abstract The biological activities of propolis samples are the result of many bioactive compounds present in the propolis. The aim of the present study was to determine the various chemical compounds of some selected propolis samples collected from Palestine and Morocco by the High-Performance Liquid Chromatography-Photodiode Array Detection (HPLC-PDA) method, as well as the antioxidant and antibacterial activities of this bee product. The chemical analysis of propolis samples by HPLC-PDA shows the cinnamic acid content in the Palestinian sample is higher compared to that in Moroccan propolis. The results of antioxidant activity demonstrated an important free radical scavenging activity (2,2-Diphenyl-1-picrylhydrazyl (DPPH); 2,2 '-azino-bis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) and reducing power assays) with EC50 values ranging between 0.02 +/- 0.001 and 0.14 +/- 0.01 mg/mL. Additionally, all tested propolis samples possessed a moderate antibacterial activity against bacterial strains. Notably, Minimum Inhibitory Concentrations (MICs) values ranged from 0.31 to 2.50 mg/mL for Gram-negative bacterial strains and from 0.09 to 0.125 mg/mL for Gram-positive bacterial strains. The S2 sample from Morocco and the S4 sample from Palestine had the highest content of polyphenol level. Thus, the strong antioxidant and antibacterial properties were apparently due to the high total phenolic and flavone/flavonol contents in the samples. As a conclusion, the activities of propolis samples collected from both countries are similar, while the cinnamic acid in the Palestinian samples was more than that of the Moroccan samples. en
dc.format.extent 17
dc.language.iso eng
dc.relation.ispartof Molecules
dc.rights en
dc.subject propolis en
dc.subject phenolic profile en
dc.subject HPLC en
dc.subject antioxidant and antibacterial activity en
dc.subject CAPACITY en
dc.subject HONEY en
dc.subject 116 Chemical sciences en
dc.title Determination of Phenolic Compounds in Various Propolis Samples Collected from an African and an Asian Region and Their Impact on Antioxidant and Antibacterial Activities en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.3390/molecules26154589
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
dc.contributor.pbl

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