Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder

Show full item record



Permalink

http://hdl.handle.net/10138/333426

Citation

Mazumder , A H , Barnett , J , Lindberg , N , Torniainen-Holm , M , Lähteenvuo , M , Lahdensuo , K , Kerkelä , M , Hietala , J , Isometsä , E T , Kampman , O , Kieseppä , T , Jukuri , T , Häkkinen , K , Cederlöf , E , Haaki , W , Kajanne , R , Wegelius , A , Männynsalo , T , Niemi-Pynttäri , J , Suokas , K , Lönnqvist , J , Niemelä , S , Tiihonen , J , Paunio , T , Palotie , A , Suvisaari , J & Veijola , J 2021 , ' Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder ' , Brain Sciences , vol. 11 , no. 6 , 688 . https://doi.org/10.3390/brainsci11060688

Title: Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder
Author: Mazumder, Atiqul Haq; Barnett, Jennifer; Lindberg, Nina; Torniainen-Holm, Minna; Lähteenvuo, Markku; Lahdensuo, Kaisla; Kerkelä, Martta; Hietala, Jarmo; Isometsä, Erkki Tapio; Kampman, Olli; Kieseppä, Tuula; Jukuri, Tuomas; Häkkinen, Katja; Cederlöf, Erik; Haaki, Willehard; Kajanne, Risto; Wegelius, Asko; Männynsalo, Teemu; Niemi-Pynttäri, Jussi; Suokas, Kimmo; Lönnqvist, Jouko; Niemelä, Solja; Tiihonen, Jari; Paunio, Tiina; Palotie, Aarno; Suvisaari, Jaana; Veijola, Juha
Contributor: University of Helsinki, HUS Psychiatry
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Department of Psychiatry
University of Helsinki, Staff Services
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Genomics of Neurological and Neuropsychiatric Disorders
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, HUS Psychiatry
University of Helsinki, HUS Psychiatry
University of Helsinki, Centre of Excellence in Complex Disease Genetics
Date: 2021-06
Language: eng
Number of pages: 16
Belongs to series: Brain Sciences
ISSN: 2076-3425
URI: http://hdl.handle.net/10138/333426
Abstract: The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia, and schizoaffective disorder and alcohol use might aggravate this phenomenon. The study population included 3362 individuals from Finland with diagnoses of schizophrenia or schizoaffective disorder. Hazardous drinking was screened with the AUDIT-C (Alcohol Use Disorders Identification Test for Consumption) screening tool. Alcohol use disorder (AUD) diagnoses were obtained from national registrar data. Participants performed two computerized tasks from the Cambridge Automated Neuropsychological Test Battery (CANTAB) on a tablet computer: The Five-Choice Serial Reaction Time Task (5-CSRTT) or the reaction time (RT) test and the Paired Associative Learning (PAL) test. The association between alcohol use and the RT and PAL tests was analyzed with log-linear regression and logistic regression, respectively. After adjustment for age, education, housing status, and the age at which the respondents had their first psychotic episodes, hazardous drinking was associated with a lower median RT in females and less variable RT in males, while AUD was associated with a poorer PAL test performance in terms of the total errors adjusted scores (TEASs) in females. Our findings of positive associations between alcohol and cognition in schizophrenia and schizoaffective disorder are unique.
Subject: cognition
visual memory
reaction time
alcohol
schizophrenia
schizoaffective disorder
SUBSTANCE USE DISORDER
CORONARY-HEART-DISEASE
COGNITIVE FUNCTION
PSYCHIATRIC OUTPATIENTS
OLDER-ADULTS
LATE-LIFE
CONSUMPTION
RISK
COHORT
ASSOCIATION
3112 Neurosciences
3124 Neurology and psychiatry
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
brainsci_11_00688_v2_1_.pdf 748.1Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record