Surgical treatment of skeletal metastases in proximal tibia: a multicenter case series of 74 patients

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Kilk , K , Ehne , J , Stevenson , J D , Kask , G , Nieminen , J , Wedin , R , Parry , M C & Laitinen , M K 2021 , ' Surgical treatment of skeletal metastases in proximal tibia: a multicenter case series of 74 patients ' , Acta Orthopaedica , vol. 92 , no. 3 , pp. 352-357 . https://doi.org/10.1080/17453674.2020.1866242

Title: Surgical treatment of skeletal metastases in proximal tibia: a multicenter case series of 74 patients
Author: Kilk, Kaarel; Ehne, Jessica; Stevenson, Jonathan D; Kask, Gilber; Nieminen, Jyrki; Wedin, Rikard; Parry, Michael C; Laitinen, Minna K
Contributor: University of Helsinki, HUS Musculoskeletal and Plastic Surgery
University of Helsinki, Clinicum
University of Helsinki, HUS Musculoskeletal and Plastic Surgery
Date: 2021-05-04
Language: eng
Number of pages: 6
Belongs to series: Acta Orthopaedica
ISSN: 1745-3674
URI: http://hdl.handle.net/10138/333559
Abstract: Background and purpose - The proximal tibia is a rare site for metastatic bone disease and is a challenging anatomical site to manage due to the proximity to the knee joint and poor soft tissue envelope. We investigated implant survival and complications of different surgical strategies in the treatment of proximal tibia pathological fractures. Patients and methods - The study comprised a 4 medical center, retrospective analysis of 74 patients surgically treated for metastases of the proximal tibia. Patient records were reviewed to identify outcome, incidence, and type of complications as well as contributing factors. Results - Reconstruction techniques comprised cement-augmented osteosynthesis (n = 33), tumor prosthesis (n = 31), and total knee arthroplasty with long cemented stems (n = 10). Overall implant survival was 88% at 6 months and 1 year, and 67% at 3 years. After stratification by technique, the implant survival was 82% and 71% at 1 and 3 years with tumor prosthesis, 100% at 1 and 3 years with total knee arthroplasty, and 91% at 1 year and 47% at 3 years with osteosynthesis. Preoperative radiotherapy decreased implant survival. Complications were observed in 19/74 patients. Treatment complications led to amputation in 5 patients. Interpretation - In this study, the best results were seen with both types of prothesis reconstructions, with good implant survival, when compared with treatment with osteosynthesis. However, patients treated with tumor prosthesis showed an increased incidence of postoperative infection, which resulted in poor implant survival. Osteosynthesis with cement is a good alternative for patients with short expected survival whereas endoprosthetic replacement achieved good medium-term results.
Subject: 3126 Surgery, anesthesiology, intensive care, radiology
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