Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder

Show simple item record

dc.contributor.author Mazumder, Atiqul Haq
dc.contributor.author Barnett, Jennifer
dc.contributor.author Isometsä, Erkki Tapio
dc.contributor.author Lindberg, Nina
dc.contributor.author Torniainen-Holm, Minna
dc.contributor.author Lähteenvuo, Markku
dc.contributor.author Lahdensuo, Kaisla
dc.contributor.author Kerkelä, Martta
dc.contributor.author Ahola-Olli, Ari
dc.contributor.author Hietala, Jarmo
dc.contributor.author Kampman, Olli
dc.contributor.author Kieseppä, Tuula
dc.contributor.author Jukuri, Tuomas
dc.contributor.author Häkkinen, Katja
dc.contributor.author Cederlöf, Erik
dc.contributor.author Haaki, Willehard
dc.contributor.author Kajanne, Risto
dc.contributor.author Wegelius, Asko
dc.contributor.author Männynsalo, Teemu
dc.contributor.author Niemi-Pynttäri, Jussi
dc.contributor.author Suokas, Kimmo
dc.contributor.author Lönnqvist, Jouko
dc.contributor.author Tiihonen, Jari
dc.contributor.author Paunio, Tiina
dc.contributor.author Vainio, Seppo Juhani
dc.contributor.author Palotie, Aarno
dc.contributor.author Niemelä, Solja
dc.contributor.author Suvisaari, Jaana
dc.contributor.author Veijola, Juha
dc.date.accessioned 2021-09-09T13:40:11Z
dc.date.available 2021-09-09T13:40:11Z
dc.date.issued 2021-08-30
dc.identifier.citation Mazumder, A.H.; Barnett, J.; Isometsä, E.T.; Lindberg, N.; Torniainen-Holm, M.; Lähteenvuo, M.; Lahdensuo, K.; Kerkelä, M.; Ahola-Olli, A.; Hietala, J.; Kampman, O.; Kieseppä, T.; Jukuri, T.; Häkkinen, K.; Cederlöf, E.; Haaki, W.; Kajanne, R.; Wegelius, A.; Männynsalo, T.; Niemi-Pynttäri, J.; Suokas, K.; Lönnqvist, J.; Tiihonen, J.; Paunio, T.; Vainio, S.J.; Palotie, A.; Niemelä, S.; Suvisaari, J.; Veijola, J. Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder. Brain Sci. 2021, 11, 1154.
dc.identifier.uri http://hdl.handle.net/10138/334216
dc.description.abstract The purpose of this study was to explore the association of cognition with hazardous drinking and alcohol-related disorder in persons with bipolar disorder (BD). The study population included 1268 persons from Finland with bipolar disorder. Alcohol use was assessed through hazardous drinking and alcohol-related disorder including alcohol use disorder (AUD). Hazardous drinking was screened with the Alcohol Use Disorders Identification Test for Consumption (AUDIT-C) screening tool. Alcohol-related disorder diagnoses were obtained from the national registrar data. Participants performed two computerized tasks from the Cambridge Automated Neuropsychological Test Battery (CANTAB) on A tablet computer: the 5-choice serial reaction time task, or reaction time (RT) test and the Paired Associative Learning (PAL) test. Depressive symptoms were assessed with the Mental Health Inventory with five items (MHI-5). However, no assessment of current manic symptoms was available. Association between RT-test and alcohol use was analyzed with log-linear regression, and eβ with 95% confidence intervals (CI) are reported. PAL first trial memory score was analyzed with linear regression, and β with 95% CI are reported. PAL total errors adjusted was analyzed with logistic regression and odds ratios (OR) with 95% CI are reported. After adjustment of age, education, housing status and depression, hazardous drinking was associated with lower median and less variable RT in females while AUD was associated with a poorer PAL test performance in terms of the total errors adjusted scores in females. Our findings of positive associations between alcohol use and cognition in persons with bipolar disorder are difficult to explain because of the methodological flaw of not being able to separately assess only participants in euthymic phase.
dc.publisher Multidisciplinary Digital Publishing Institute
dc.title Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder
dc.date.updated 2021-09-09T13:40:11Z
dc.type.uri http://purl.org/eprint/entityType/JournalArticle
dc.type.uri http://purl.org/eprint/entityType/Expression
dc.type.uri http://purl.org/eprint/entityType/Expression

Files in this item

Total number of downloads: Loading...

Files Size Format View
brainsci-11-01154-v2.pdf 3.219Mb PDF View/Open

This item appears in the following Collection(s)

Show simple item record