Association between overall diet quality and postmenopausal breast cancer risk in five Finnish cohort studies

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Männistö , S , Harald , K , Härkänen , T , Maukonen , M , Eriksson , J G , Heikkinen , S , Jousilahti , P , Kaartinen , N E , Kanerva , N , Knekt , P , Koskinen , S , Laaksonen , M A , Malila , N , Rissanen , H & Pitkäniemi , J 2021 , ' Association between overall diet quality and postmenopausal breast cancer risk in five Finnish cohort studies ' , Scientific Reports , vol. 11 , no. 1 , 16718 . https://doi.org/10.1038/s41598-021-95773-2

Title: Association between overall diet quality and postmenopausal breast cancer risk in five Finnish cohort studies
Author: Männistö, Satu; Harald, Kennet; Härkänen, Tommi; Maukonen, Mirkka; Eriksson, Johan G.; Heikkinen, Sanna; Jousilahti, Pekka; Kaartinen, Niina E.; Kanerva, Noora; Knekt, Paul; Koskinen, Seppo; Laaksonen, Maarit A.; Malila, Nea; Rissanen, Harri; Pitkäniemi, Janne
Contributor organization: Clinicum
Research Programs Unit
Johan Eriksson / Principal Investigator
Department of General Practice and Primary Health Care
Department of Food and Nutrition
Department of Public Health
Date: 2021-08-18
Language: eng
Number of pages: 9
Belongs to series: Scientific Reports
ISSN: 2045-2322
DOI: https://doi.org/10.1038/s41598-021-95773-2
URI: http://hdl.handle.net/10138/335067
Abstract: There is limited evidence for any dietary factor, except alcohol, in breast cancer (BC) risk. Therefore, studies on a whole diet, using diet quality indices, can broaden our insight. We examined associations of the Nordic Diet (mNDI), Mediterranean diet (mMEDI) and Alternative Healthy Eating Index (mAHEI) with postmenopausal BC risk. Five Finnish cohorts were combined including 6374 postmenopausal women with dietary information. In all, 8-9 dietary components were aggregated in each index, higher total score indicating higher adherence to a healthy diet. Cox proportional hazards regression was used to estimate the combined hazard ratio (HR) and 95% confidence interval (CI) for BC risk. During an average 10-year follow-up period, 274 incident postmenopausal BC cases were diagnosed. In multivariable models, the HR for highest vs. lowest quintile of index was 0.67 (95 %CI 0.48-1.01) for mNDI, 0.88 (0.59-1.30) for mMEDI and 0.89 (0.60-1.32) for mAHEI. In this combined dataset, a borderline preventive finding of high adherence to mNDI on postmenopausal BC risk was found. Of the indices, mNDI was more based on the local food culture than the others. Although a healthy diet has beneficially been related to several chronic diseases, the link with the etiology of postmenopausal BC does not seem to be that obvious.
Subject: BALTIC SEA DIET
FOOD FREQUENCY QUESTIONNAIRE
HEALTHY NORDIC DIET
MEDITERRANEAN DIET
ADHERENCE
DISEASE
METAANALYSIS
VALIDITY
WOMEN
INDEX
3121 General medicine, internal medicine and other clinical medicine
3143 Nutrition
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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