Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort

Show full item record



Permalink

http://hdl.handle.net/10138/335139

Citation

Loo , E X L , Zhang , Y , Yap , Q V , Yu , G , Soh , S E , Loy , S L , Lau , H X , Chan , S-Y , Shek , L P-C , Luo , Z-C , Yap , F K P , Tan , K H , Chong , Y S , Zhang , J & Eriksson , J G 2021 , ' Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort ' , BMC Pregnancy and Childbirth , vol. 21 , no. 1 , 566 . https://doi.org/10.1186/s12884-021-04036-5

Title: Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort
Author: Loo, Evelyn Xiu Ling; Zhang, Yuqing; Yap, Qai Ven; Yu, Guoqi; Soh, Shu E.; Loy, See Ling; Lau, Hui Xing; Chan, Shiao-Yng; Shek, Lynette Pei-Chi; Luo, Zhong-Cheng; Yap, Fabian Kok Peng; Tan, Kok Hian; Chong, Yap Seng; Zhang, Jun; Eriksson, Johan Gunnar
Contributor: University of Helsinki, Clinicum
Date: 2021-08-18
Language: eng
Number of pages: 12
Belongs to series: BMC Pregnancy and Childbirth
ISSN: 1471-2393
URI: http://hdl.handle.net/10138/335139
Abstract: Background Gestational diabetes mellitus (GDM) has been associated with adverse health outcomes for mothers and offspring. Prevalence of GDM differs by country/region due to ethnicity, lifestyle and diagnostic criteria. We compared GDM rates and risk factors in two Asian cohorts using the 1999 WHO and the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Methods The Shanghai Birth Cohort (SBC) and the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort are prospective birth cohorts. Information on sociodemographic characteristics and medical history were collected from interviewer-administered questionnaires. Participants underwent a 2-h 75-g oral glucose tolerance test at 24-28 weeks gestation. Logistic regressions were performed. Results Using the 1999 WHO criteria, the prevalence of GDM was higher in GUSTO (20.8%) compared to SBC (16.6%) (p = 0.046). Family history of hypertension and alcohol consumption were associated with higher odds of GDM in SBC than in GUSTO cohort while obesity was associated with higher odds of GDM in GUSTO. Using the IADPSG criteria, the prevalence of GDM was 14.3% in SBC versus 12.0% in GUSTO. A history of GDM was associated with higher odds of GDM in GUSTO than in SBC, while being overweight, alcohol consumption and family history of diabetes were associated with higher odds of GDM in SBC. Conclusions We observed several differential risk factors of GDM among ethnic Chinese women living in Shanghai and Singapore. These findings might be due to heterogeneity of GDM reflected in diagnostic criteria as well as in unmeasured genetic, lifestyle and environmental factors.
Subject: Asian
Gestational diabetes mellitus
International Association of Diabetes and Pregnancy Study Groups
World Health Organisation
GUSTO
Shanghai birth cohort
GLUCOSE-TOLERANCE TEST
RISK-FACTORS
WEIGHT-GAIN
MELLITUS
OBESITY
ASSOCIATION
POPULATIONS
PREVALENCE
PREGNANCY
DIAGNOSIS
3123 Gynaecology and paediatrics
3121 General medicine, internal medicine and other clinical medicine
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
Comparative_epidemiology_of_gestational...pdf 7.953Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record