Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort

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dc.contributor.author Loo, Evelyn Xiu Ling
dc.contributor.author Zhang, Yuqing
dc.contributor.author Yap, Qai Ven
dc.contributor.author Yu, Guoqi
dc.contributor.author Soh, Shu E.
dc.contributor.author Loy, See Ling
dc.contributor.author Lau, Hui Xing
dc.contributor.author Chan, Shiao-Yng
dc.contributor.author Shek, Lynette Pei-Chi
dc.contributor.author Luo, Zhong-Cheng
dc.contributor.author Yap, Fabian Kok Peng
dc.contributor.author Tan, Kok Hian
dc.contributor.author Chong, Yap Seng
dc.contributor.author Zhang, Jun
dc.contributor.author Eriksson, Johan Gunnar
dc.date.accessioned 2021-10-11T12:06:02Z
dc.date.available 2021-10-11T12:06:02Z
dc.date.issued 2021-08-18
dc.identifier.citation Loo , E X L , Zhang , Y , Yap , Q V , Yu , G , Soh , S E , Loy , S L , Lau , H X , Chan , S-Y , Shek , L P-C , Luo , Z-C , Yap , F K P , Tan , K H , Chong , Y S , Zhang , J & Eriksson , J G 2021 , ' Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort ' , BMC Pregnancy and Childbirth , vol. 21 , no. 1 , 566 . https://doi.org/10.1186/s12884-021-04036-5
dc.identifier.other PURE: 169349107
dc.identifier.other PURE UUID: 9d495f55-9238-417b-8176-3fe2ef893a00
dc.identifier.other WOS: 000686683800005
dc.identifier.uri http://hdl.handle.net/10138/335139
dc.description.abstract Background Gestational diabetes mellitus (GDM) has been associated with adverse health outcomes for mothers and offspring. Prevalence of GDM differs by country/region due to ethnicity, lifestyle and diagnostic criteria. We compared GDM rates and risk factors in two Asian cohorts using the 1999 WHO and the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Methods The Shanghai Birth Cohort (SBC) and the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort are prospective birth cohorts. Information on sociodemographic characteristics and medical history were collected from interviewer-administered questionnaires. Participants underwent a 2-h 75-g oral glucose tolerance test at 24-28 weeks gestation. Logistic regressions were performed. Results Using the 1999 WHO criteria, the prevalence of GDM was higher in GUSTO (20.8%) compared to SBC (16.6%) (p = 0.046). Family history of hypertension and alcohol consumption were associated with higher odds of GDM in SBC than in GUSTO cohort while obesity was associated with higher odds of GDM in GUSTO. Using the IADPSG criteria, the prevalence of GDM was 14.3% in SBC versus 12.0% in GUSTO. A history of GDM was associated with higher odds of GDM in GUSTO than in SBC, while being overweight, alcohol consumption and family history of diabetes were associated with higher odds of GDM in SBC. Conclusions We observed several differential risk factors of GDM among ethnic Chinese women living in Shanghai and Singapore. These findings might be due to heterogeneity of GDM reflected in diagnostic criteria as well as in unmeasured genetic, lifestyle and environmental factors. en
dc.format.extent 12
dc.language.iso eng
dc.relation.ispartof BMC Pregnancy and Childbirth
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Asian
dc.subject Gestational diabetes mellitus
dc.subject International Association of Diabetes and Pregnancy Study Groups
dc.subject World Health Organisation
dc.subject GUSTO
dc.subject Shanghai birth cohort
dc.subject GLUCOSE-TOLERANCE TEST
dc.subject RISK-FACTORS
dc.subject WEIGHT-GAIN
dc.subject MELLITUS
dc.subject OBESITY
dc.subject ASSOCIATION
dc.subject POPULATIONS
dc.subject PREVALENCE
dc.subject PREGNANCY
dc.subject DIAGNOSIS
dc.subject 3123 Gynaecology and paediatrics
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort en
dc.type Article
dc.contributor.organization Clinicum
dc.contributor.organization Research Programs Unit
dc.contributor.organization Johan Eriksson / Principal Investigator
dc.contributor.organization Department of General Practice and Primary Health Care
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1186/s12884-021-04036-5
dc.relation.issn 1471-2393
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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