Both lean and fat body mass associate with blood pressure

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dc.contributor.author Korhonen, Päivi E.
dc.contributor.author Mikkola, Tuija
dc.contributor.author Kautiainen, Hannu
dc.contributor.author Eriksson, Johan G.
dc.date.accessioned 2021-10-12T07:56:01Z
dc.date.available 2021-10-12T07:56:01Z
dc.date.issued 2021-09
dc.identifier.citation Korhonen , P E , Mikkola , T , Kautiainen , H & Eriksson , J G 2021 , ' Both lean and fat body mass associate with blood pressure ' , European Journal of Internal Medicine , vol. 91 , pp. 40-44 . https://doi.org/10.1016/j.ejim.2021.04.025
dc.identifier.other PURE: 169374809
dc.identifier.other PURE UUID: 64760265-7ab2-43ac-a7e7-d0f103c6ae92
dc.identifier.other WOS: 000690383400008
dc.identifier.uri http://hdl.handle.net/10138/335178
dc.description.abstract High body mass index (BMI) is known to be associated with elevated blood pressure (BP). The present study aims to determine the relative importance of the two components of BMI, fat mass and lean body mass index, on BP levels. We assessed body composition with bioimpedance and performed 24 hour ambulatory BP measurements in 534 individuals (mean age 61 +/- 3 years) who had no cardiovascular medication. Fat mass index and lean mass index were calculated analogously to BMI as fat mass or lean body mass (kg) divided by the square of height (m2). Both fat mass index and lean mass index showed a positive, small to moderate relationship with all 24 hour BP components independently of age, sex, smoking, and leisure-time physical activity. There were no interaction effects between fat mass index and lean mass index on the mean BP levels. Adult lean body mass is a significant determinant of BP levels with an equal, albeit small to moderate magnitude as fat mass. Relatively high amount of muscle mass may not be beneficial to cardiovascular health. en
dc.format.extent 5
dc.language.iso eng
dc.relation.ispartof European Journal of Internal Medicine
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Blood pressure
dc.subject Body mass index
dc.subject Lean body mass
dc.subject Fat mass
dc.subject MENDELIAN RANDOMIZATION
dc.subject RISK
dc.subject HYPERTENSION
dc.subject INDEX
dc.subject OBESITY
dc.subject IMPACT
dc.subject ADIPOSITY
dc.subject EXERCISE
dc.subject DISEASE
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Both lean and fat body mass associate with blood pressure en
dc.type Article
dc.contributor.organization Clinicum
dc.contributor.organization Johan Eriksson / Principal Investigator
dc.contributor.organization Department of General Practice and Primary Health Care
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.ejim.2021.04.025
dc.relation.issn 0953-6205
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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