Severe deforming dermatitis in a kitten caused by Caryospora bigenetica

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Saari , S , Schildt , K , Malkamäki , S , Andersin , U & Sukura , A 2021 , ' Severe deforming dermatitis in a kitten caused by Caryospora bigenetica ' , Acta Veterinaria Scandinavica , vol. 63 , no. 1 , 39 . https://doi.org/10.1186/s13028-021-00604-z

Title: Severe deforming dermatitis in a kitten caused by Caryospora bigenetica
Author: Saari, Seppo; Schildt, Kirsti; Malkamäki, Sanna; Andersin, Ulla; Sukura, Antti
Other contributor: University of Helsinki, Veterinary Biosciences
University of Helsinki, Faculty of Veterinary Medicine




Date: 2021-10-10
Language: eng
Number of pages: 7
Belongs to series: Acta Veterinaria Scandinavica
ISSN: 0044-605X
DOI: https://doi.org/10.1186/s13028-021-00604-z
URI: http://hdl.handle.net/10138/335516
Abstract: Background Caryospora bigenetica is an intracellular protozoan parasite, which in its primary hosts, typically snakes, is found it the intestine. Extraintestinal multiplication with the development of tissue cysts takes place in secondary hosts, which are normally prey for snakes. Natural infection in domestic animals has been reported only in dogs; this is the first report of C. bigenetica infection in a cat. Case presentation A stray kitten developed nodular dermatitis after being adopted by a shelter. Firm swelling, nodules, and crusts were present mainly on the nasal bridge, eyelids, and pinnae. Histopathology and cytology revealed severe pyogranulomatous inflammation with abundant intracellular organisms suggestive of apicomplexan protozoa. Treatment with clindamycin 13 mg/kg twice daily was initiated, but the cat was euthanized because of the worsening condition. Transmission electron microscopy confirmed parasite's apicomplexan origin postmortem, and the causative agent was identified as C. bigenetica by polymerase chain reaction and DNA sequencing. Conclusions We present the first case of a naturally occurring infection with C. bigenetica in a cat. Although the definitive etiological diagnosis relied on molecular identification, the abundance of unsporulated oocysts and caryocysts and the parasite's effective reproduction within macrophages and in several other cell types might have enabled differentiation from other protozoal infections and allowed a presumptive diagnosis through cytology and histopathology.
Subject: Apicomplexan
Caryospora
Cytology
Dermatitis
Feline
Histopathology
Protozoa
CUTANEOUS TOXOPLASMOSIS
CAT
413 Veterinary science
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