Isolation precautions cause minor delays in diagnostics and treatment of non-COVID patients

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dc.contributor.author Paajanen, J.
dc.contributor.author Mäkinen, L. K.
dc.contributor.author Suikkila, A.
dc.contributor.author Rehell, M.
dc.contributor.author Javanainen, M.
dc.contributor.author Lindahl, A.
dc.contributor.author Kekäläinen, E.
dc.contributor.author Kurkela, S.
dc.contributor.author Halmesmäki, K.
dc.contributor.author Anttila, V. J.
dc.contributor.author Lamminmäki, S.
dc.date.accessioned 2021-10-28T08:47:01Z
dc.date.available 2021-10-28T08:47:01Z
dc.date.issued 2021-12
dc.identifier.citation Paajanen , J , Mäkinen , L K , Suikkila , A , Rehell , M , Javanainen , M , Lindahl , A , Kekäläinen , E , Kurkela , S , Halmesmäki , K , Anttila , V J & Lamminmäki , S 2021 , ' Isolation precautions cause minor delays in diagnostics and treatment of non-COVID patients ' , Infection Prevention in Practice , vol. 3 , no. 4 , 100178 , pp. 8 . https://doi.org/10.1016/j.infpip.2021.100178
dc.identifier.other PURE: 169851804
dc.identifier.other PURE UUID: ebe343de-6c7e-4b13-8e0d-af6da2448537
dc.identifier.other Scopus: 85117096314
dc.identifier.other ORCID: /0000-0001-6045-108X/work/102234813
dc.identifier.other ORCID: /0000-0003-1553-1915/work/102237472
dc.identifier.other ORCID: /0000-0003-0741-4989/work/108072021
dc.identifier.uri http://hdl.handle.net/10138/335781
dc.description Publisher Copyright: © 2021
dc.description.abstract Background: Isolation precautions are essential prevent spread of COVID-19 infection but may have a negative impact on inpatient care. The impact of these measures on non-COVID-19 patients remains largely unexplored. Aim: This study aimed to investigate diagnostic and treatment delays related to isolation precautions, the associated patient outcome, and the predisposing risk factors for delays. Methods: This observational study was conducted in seven Helsinki region hospitals during the first wave of the COVID-19 pandemic in Finland. The study used data on all non-COVID-19 inpatients, who were initially isolated due to suspected COVID-19, to estimate whether isolation precautions resulted in diagnostic or treatment delays. Results: Out of 683 non-COVID-19 patients, 33 (4.8%) had delays related to isolation precautions. Clinical condition deteriorated non-fatally in seven (1.0%) patients. The following events were associated with an increased risk of treatment or a diagnostic delay: more than three ward transfers (P = 0.025); referral to an incorrect speciality in the emergency department (P = 0.004); more than three SARS-CoV-2 RT-PCR tests performed (P = 0.022); and where cancer was the final diagnosis (P = 0.018). In contrast, lower respiratory tract symptoms (P = 0.013) decreased the risk. Conclusions: The use of isolation precautions for patients who did not have COVID-19 had minor negative effects on patient outcomes. The present study underlines the importance of targeting diagnostic efforts to patients with unspecified symptoms and to those with a negative SARS-CoV-2 test result. Thorough investigations to achieve an accurate diagnosis improves the prognosis of patients and facilitates appropriate targeting of hospital resources. en
dc.language.iso eng
dc.relation.ispartof Infection Prevention in Practice
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject COVID-19
dc.subject Isolation precaution
dc.subject Non-COVID-19
dc.subject Patient outcome
dc.subject Treatment delay
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.subject 11832 Microbiology and virology
dc.title Isolation precautions cause minor delays in diagnostics and treatment of non-COVID patients en
dc.type Article
dc.contributor.organization HUS Heart and Lung Center
dc.contributor.organization Keuhkosairauksien yksikkö
dc.contributor.organization Korva-, nenä- ja kurkkutautien klinikka
dc.contributor.organization Department of Ophthalmology and Otorhinolaryngology
dc.contributor.organization HUS Head and Neck Center
dc.contributor.organization HUS Abdominal Center
dc.contributor.organization Medicum
dc.contributor.organization HUSLAB
dc.contributor.organization Department of Bacteriology and Immunology
dc.contributor.organization TRIMM - Translational Immunology Research Program
dc.contributor.organization HUS Diagnostic Center
dc.contributor.organization Olli Pekka Vapalahti / Principal Investigator
dc.contributor.organization Viral Zoonosis Research Unit
dc.contributor.organization Department of Virology
dc.contributor.organization Verisuonikirurgian yksikkö
dc.contributor.organization HUS Inflammation Center
dc.contributor.organization Infektiosairauksien yksikkö
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.infpip.2021.100178
dc.relation.issn 2590-0889
dc.rights.accesslevel openAccess
dc.type.version publishedVersion
dc.identifier.url http://www.scopus.com/inward/record.url?scp=85117096314&partnerID=8YFLogxK

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