Switching to the Dry-Powder Inhaler Easyhaler® : A Narrative Review of the Evidence

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http://hdl.handle.net/10138/336592

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Lavorini , F , Chudek , J , Gálffy , G , Pallarés-Sanmartin , A , Pelkonen , A S , Rytilä , P , Syk , J , Szilasi , M , Tamási , L , Xanthopoulos , A & Haahtela , T 2021 , ' Switching to the Dry-Powder Inhaler Easyhaler ® : A Narrative Review of the Evidence ' , Pulmonary Therapy , vol. 7 , no. 2 , pp. 409-427 . https://doi.org/10.1007/s41030-021-00174-5

Title: Switching to the Dry-Powder Inhaler Easyhaler® : A Narrative Review of the Evidence
Author: Lavorini, Federico; Chudek, Jerzy; Gálffy, Gabriella; Pallarés-Sanmartin, Abel; Pelkonen, Anna S.; Rytilä, Paula; Syk, Jörgen; Szilasi, Maria; Tamási, Lilla; Xanthopoulos, Athanasios; Haahtela, Tari
Other contributor: University of Helsinki, HUS Inflammation Center
University of Helsinki, Department of Dermatology, Allergology and Venereology
University of Helsinki, HUS Inflammation Center

Date: 2021-12
Language: eng
Number of pages: 19
Belongs to series: Pulmonary Therapy
ISSN: 2364-1754
DOI: https://doi.org/10.1007/s41030-021-00174-5
URI: http://hdl.handle.net/10138/336592
Abstract: Asthma and chronic obstructive pulmonary disease (COPD) are major causes of morbidity and mortality worldwide. Optimal control of these conditions is a constant challenge for both physicians and patients. Poor inhaler practice is widespread and is a substantial contributing factor to the suboptimal clinical control of both conditions. The practicality, dependability, and acceptability of different inhalers influence the overall effectiveness and success of inhalation therapy. In this paper, experts from various European countries (Finland, Germany, Hungary, Italy, Poland, Spain, and Sweden) address inhaler selection with special focus on the Easyhaler® device, a high- or medium–high resistance dry-powder inhaler (DPI). The evidence examined indicates that use of the Easyhaler is associated with effective control of asthma or COPD, as shown by the generally accepted indicators of treatment success. Moreover, the Easyhaler is widely accepted by patients, is reported to be easy to learn and teach, and is associated with patient adherence. These advantages help patient education regarding correct inhaler use and the rational selection of drugs and devices. We conclude that switching inhaler device to the Easyhaler may improve asthma and COPD control without causing any additional risks. In an era of climate change, switching from pressurized metered-dose inhalers to DPIs is also a cost-effective way to reduce emissions of greenhouse gases. [MediaObject not available: see fulltext.].
Subject: Adherence
Asthma
Compliance
COPD
Dry-powder inhaler
Easyhaler
Patient-centered outcomes
Pressurized metered-dose inhaler
Respiratory function
SALBUTAMOL
EFFICACY
FLOW-RATE
CHILDREN
IN-VITRO
REAL-LIFE
ASTHMA
DEVICES
PULMONARY-DISEASE COPD
OUTCOMES
3121 General medicine, internal medicine and other clinical medicine
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