Death in Sauna Associated With a Transdermal Fentanyl Patch

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Pysyväisosoite

http://hdl.handle.net/10138/336956

Lähdeviite

Kriikku , P , Ojanpera , I & Lunetta , P 2020 , ' Death in Sauna Associated With a Transdermal Fentanyl Patch ' , The American Journal of Forensic Medicine and Pathology , vol. 41 , no. 4 , pp. 313-314 . https://doi.org/10.1097/PAF.0000000000000565

Julkaisun nimi: Death in Sauna Associated With a Transdermal Fentanyl Patch
Tekijä: Kriikku, Pirkko; Ojanpera, Ilkka; Lunetta, Philippe
Tekijän organisaatio: Medicum
Department of Forensic Medicine
Päiväys: 2020-12
Kieli: eng
Sivumäärä: 2
Kuuluu julkaisusarjaan: The American Journal of Forensic Medicine and Pathology
ISSN: 0195-7910
DOI-tunniste: https://doi.org/10.1097/PAF.0000000000000565
URI: http://hdl.handle.net/10138/336956
Tiivistelmä: We present a case of an accidental fatal fentanyl overdose caused by increased uptake of the drug from a transdermal patch while experiencing the heat of a sauna. The transdermal patch administers fentanyl at a relatively constant rate through the skin. However, in the subcutaneous tissue, blood circulation greatly influences the rate of this drug's systemic intake. In the present case, an elderly woman with multiple health conditions was prescribed fentanyl patches but was unaware of the risks associated with external heat sources when one wears the patch. She was found dead in the sauna with a postmortem femoral blood concentration of fentanyl that was elevated (15 mu g/L). The cause of death was determined to be fatal poisoning by fentanyl with the contributing factor of external heat from the sauna. Risks associated with transdermal administration of a potent opioid-like fentanyl are widely described in the scientific literature and described in the manufacturer's summary of product characteristics. Physicians and pharmacists should take particular care to ensure that patients understand these risks.
Avainsanat: fentanyl
transdermal patch
opioid intoxication
sauna
319 Forensic science and other medical sciences
Vertaisarvioitu: Ei
Tekijänoikeustiedot: cc_by_nc
Pääsyrajoitteet: openAccess
Rinnakkaistallennettu versio: acceptedVersion


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