Does Protocol Make a Difference? Comparison of Two Prostate Cancer Active Surveillance Cohorts : A Non-protocol-based Follow-up and a Protocol-based Contemporary Follow-up

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Kalalahti , I , Vasarainen , H , Erickson , A M , Siipola , A , Tikkinen , K A O & Rannikko , A 2021 , ' Does Protocol Make a Difference? Comparison of Two Prostate Cancer Active Surveillance Cohorts : A Non-protocol-based Follow-up and a Protocol-based Contemporary Follow-up ' , European urology open science , vol. 34 , pp. 33-40 . https://doi.org/10.1016/j.euros.2021.09.016

Title: Does Protocol Make a Difference? Comparison of Two Prostate Cancer Active Surveillance Cohorts : A Non-protocol-based Follow-up and a Protocol-based Contemporary Follow-up
Author: Kalalahti, Inari; Vasarainen, Hanna; Erickson, Andrew M.; Siipola, Arttu; Tikkinen, Kari A. O.; Rannikko, Antti
Contributor organization: HUS Abdominal Center
Urologian yksikkö
Research Program in Systems Oncology
Department of Surgery
South Carelia Social and Health care District Eksote
HYKS erva
Clinicum
Date: 2021-12
Language: eng
Number of pages: 8
Belongs to series: European urology open science
ISSN: 2666-1691
DOI: https://doi.org/10.1016/j.euros.2021.09.016
URI: http://hdl.handle.net/10138/337330
Abstract: Background: Active surveillance (AS) is the preferred option for initial management for low-risk prostate cancer (PC). Although many AS protocols exist, there is little evidence to support one over another. Objective: To assess whether there is difference in overall (OS), prostate cancer-specific (CSS), metastasis-free (MFS), or treatment-free (TFS) survival between a strict (Prostate cancer Research International: Active Surveillance [PRIAS]) and a loose (European Randomized study of Screening for Prostate Cancer [ERSPC]) AS protocol. Design, setting, and participants: This study included two cohorts of men (n = 518) with low-risk, localized, Gleason score
Subject: Active surveillance
Prostate cancer survival
Treatment of prostate cancer
RADICAL PROSTATECTOMY
OUTCOMES
MEN
RECLASSIFICATION
COMPLICATIONS
MANAGEMENT
BIOPSIES
TRIAL
PRIAS
3126 Surgery, anesthesiology, intensive care, radiology
3122 Cancers
Peer reviewed: Yes
Rights: cc_by_nc_nd
Usage restriction: openAccess
Self-archived version: publishedVersion


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