Association between first language and SARS-CoV-2 infection rates, hospitalization, intensive care admissions and death in Finland : a population-based observational cohort study

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dc.contributor.author Holmberg, Ville
dc.contributor.author Salmi, Heli
dc.contributor.author Kattainen, Salla
dc.contributor.author Ollgren, Jukka
dc.contributor.author Kantele, Anu
dc.contributor.author Pynnönen, Juulia
dc.contributor.author Järvinen, Asko
dc.contributor.author Forsblom, Erik
dc.contributor.author Silén, Suvi
dc.contributor.author Kivivuori, Sanna Maria
dc.contributor.author Meretoja, Atte
dc.contributor.author Hästbacka, Johanna
dc.date.accessioned 2022-01-14T13:16:01Z
dc.date.available 2022-01-14T13:16:01Z
dc.date.issued 2022-01
dc.identifier.citation Holmberg , V , Salmi , H , Kattainen , S , Ollgren , J , Kantele , A , Pynnönen , J , Järvinen , A , Forsblom , E , Silén , S , Kivivuori , S M , Meretoja , A & Hästbacka , J 2022 , ' Association between first language and SARS-CoV-2 infection rates, hospitalization, intensive care admissions and death in Finland : a population-based observational cohort study ' , Clinical Microbiology and Infection , vol. 28 , no. 1 , pp. 107-113 . https://doi.org/10.1016/j.cmi.2021.08.022
dc.identifier.other PURE: 171427422
dc.identifier.other PURE UUID: 0560ee32-bc8e-4435-974b-b433b6e174ae
dc.identifier.other Scopus: 85120737067
dc.identifier.other Scopus: 85120737067
dc.identifier.other WOS: 000735207100017
dc.identifier.other ORCID: /0000-0002-3613-7231/work/106339666
dc.identifier.other ORCID: /0000-0002-5866-9634/work/106341784
dc.identifier.uri http://hdl.handle.net/10138/338628
dc.description Funding Information: VH has received a grant from Finska L?kares?llskapet. AJ has received a grant from Wilhelm och Else Stockmanns stiftelse and speaker honoraria from Astellas, GlaxoSmithKline, Sanofi, Thermo Fisher, MSD, OrionPharma and UnimedicPharma. JH has recieved grants from NordForsk, Government research funding and Kirsti och Tor Johansson's hj?rt och cancerstiftelse. The authors declare that they have no other conflicts of interest in relation to this work. This work was supported by a research grant from Finska L?kares?llskapet. Funding Information: VH has received a grant from Finska Läkaresällskapet . AJ has received a grant from Wilhelm och Else Stockmanns stiftelse and speaker honoraria from Astellas , GlaxoSmithKline , Sanofi , Thermo Fisher , MSD , OrionPharma and UnimedicPharma . JH has recieved grants from NordForsk , Government research funding and Kirsti och Tor Johansson’s hjärt och cancerstiftelse . The authors declare that they have no other conflicts of interest in relation to this work. This work was supported by a research grant from Finska Läkaresällskapet . Publisher Copyright: © 2021 The Authors
dc.description.abstract Objectives: Motivated by reports of increased risk of coronavirus disease 2019 (COVID-19) in ethnic minorities of high-income countries, we explored whether patients with a foreign first language are at an increased risk of COVID-19 infections, more serious presentations, or worse outcomes. Methods: In a retrospective observational population-based quality registry study covering a population of 1.7 million, we studied the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), admissions to specialist healthcare and the intensive care unit (ICU), and all-cause case fatality in different language groups between 27th February and 3rd August 2020 in Southern Finland. A first language other than Finnish, Swedish or Sami served as a surrogate marker for a foreign ethnic background. Results: In total, 124 240 individuals were tested, and among the 118 300 (95%) whose first language could be determined, 4005 (3.4%) were COVID-19-positive, 623 (0.5%) were admitted to specialized hospitals, and 147 (0.1%) were admitted to the ICU; 254 (0.2%) died. Those with a foreign first language had lower testing rates (348, 95%CI 340-355 versus 758, 95%CI 753-762 per 10 000, p < 0.0001), higher incidence (36, 95%CI 33-38 versus 22, 95%CI 21-23 per 10 000, p < 0.0001), and higher positivity rates (103, 95%CI 96-109 versus 29, 95%CI 28-30 per 1000, p < 0.0001). There was no significant difference in ICU admissions, disease severity at ICU admission, or ICU outcomes. Case fatality by 90 days was 7.7% in domestic cases and 1.2% in those with a foreign first language, explained by demographics (age-and sex adjusted HR 0.49, 95%CI 0.21-1.15). Conclusions: The population with a foreign first language was at an increased risk for testing positive for SARS-CoV-2, but when hospitalized they had outcomes similar to those in the native, domestic language population. This suggests that special attention should be paid to the prevention and control of infectious diseases among language minorities. (C) 2021 The Authors. Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases. en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof Clinical Microbiology and Infection
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject COVID-19
dc.subject Ethnic
dc.subject Language
dc.subject Migrants
dc.subject Minority
dc.subject SARS-CoV-2
dc.subject Vulnerable
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.subject 11832 Microbiology and virology
dc.title Association between first language and SARS-CoV-2 infection rates, hospitalization, intensive care admissions and death in Finland : a population-based observational cohort study en
dc.type Article
dc.contributor.organization Ville Holmberg's research group / Infections in Migrants
dc.contributor.organization Department of Medicine
dc.contributor.organization HUS Inflammation Center
dc.contributor.organization Infektiosairauksien yksikkö
dc.contributor.organization HUS Perioperative, Intensive Care and Pain Medicine
dc.contributor.organization Anestesiologian yksikkö
dc.contributor.organization Clinicum
dc.contributor.organization HUS Head and Neck Center
dc.contributor.organization Department of Ophthalmology and Otorhinolaryngology
dc.contributor.organization Korva-, nenä- ja kurkkutautien klinikka
dc.contributor.organization HUS Children and Adolescents
dc.contributor.organization Children's Hospital
dc.contributor.organization Helsinki University Hospital Area
dc.contributor.organization Department of Diagnostics and Therapeutics
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.cmi.2021.08.022
dc.relation.issn 1198-743X
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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